Concept

Sulfolobus solfataricus

Publications associées (12)

Centromeres are dismantled by foundational meiotic proteins Spo11 and Rec8

Meiotic processes are potentially dangerous to genome stability and could be disastrous if activated in proliferative cells. Here we show that two key meiosis-defining proteins, the topoisomerase Spo11 (which forms double-strand breaks) and the meiotic coh ...

NATURE RESEARCH2021

Chromatin Proteomics to Study Epigenetics - Challenges and Opportunities

Guido Van Mierlo

Regulation of gene expression is essential for the functioning of all eukaryotic organisms. Understanding gene expression regulation requires determining which proteins interact with regulatory elements in chromatin. MS-based analysis of chromatin has emer ...

AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC2021

Multiplexed Single-Molecule Experiments Reveal Nucleosome Invasion Dynamics of the Cas9 Genome Editor

Beat Fierz, Louise Catherine Bryan, Kristina Makasheva

Single-molecule measurements provide detailed mechanistic insights into molecular processes, for example in genome regulation where DNA access is controlled by nucleosomes and the chromatin machinery. However, real-time single-molecule observations of nucl ...

AMER CHEMICAL SOC2021

Dispersal limitations and historical factors determine the biogeography of specialized terrestrial protists

Edward Mitchell, Luca Bragazza, Mariusz Lamentowicz, Enrique Lara, Bertrand Fournier

Recent studies show that soil eukaryotic diversity is immense and dominated by micro-organisms. However, it is unclear to what extent the processes that shape the distribution of diversity in plants and animals also apply to micro-organisms. Major diversif ...

WILEY2019

Comparing the anti-bacterial performance of chlorination and electrolysis post-treatments in a hand washing water recycling system

Innovative solutions are necessary to enable the decentralized recycling of greywater for applications requiring high-quality water, such as hand washing. While physical barriers such as ultrafiltration membranes effectively prevent the passage of bacteria ...

ELSEVIER SCIENCE BV2019

Functional Characterization of Nucleoid Associated Proteins Acting as Global Transcription Factors in Mycobacterium tuberculosis

Nina Theres Odermatt

The fatal lung disease tuberculosis is caused by the airborne Mycobacterium tuberculosis, a versatile pathogen adapted to rapidly changing environments. Instead of being eradicated by phagocytic cells of its human host, bacilli tune macrophages to support ...

EPFL2017

New evidence for TiO2 uniform surfaces leading to complete bacterial reduction in the dark: Critical issues

César Pulgarin, Juan Kiwi, Danièle Laub, Sami Rtimi, Jelena Nesic

This study presents new evidence for the events leading to Escherichia coil reduction in the absence of light irradiation on TiO2-polyester (from now on TiO2-PES. By transmission electron microscopy (TEM) the diffusion of TiO2 NP's aggregates with the E. c ...

Elsevier Science Bv2014

Kinetics of membrane damage to high (HNA) and low (LNA) nucleic acid bacterial clusters in drinking water by ozone, chlorine, chlorine dioxide, monochloramine, ferrate(VI), and permanganate

Urs von Gunten

Drinking water was treated with ozone, chlorine, chlorine dioxide, monochloramine, ferrate(VI), and permanganate to investigate the kinetics of membrane damage of native drinking water bacterial cells. Membrane damage was measured by flow cytometry using a ...

2011

The kinetic parameters and energy cost of the Hsp70 chaperone as a polypeptide unfoldase

Paolo De Los Rios, Pierre Goloubinoff

Hsp70-Hsp40-NEF and possibly Hsp100 are the only known molecular chaperones that can use the energy of ATP to convert stably pre-aggregated polypeptides into natively refolded proteins. However, the kinetic parameters and ATP costs have remained elusive be ...

Nature Publishing Group2010

Mécanismes d'action du TiO2 illuminé sur Escherichia Coli

Gaëtan Gogniat

The increase of bacterial resistance against various disinfection processes is a worrying phenomenon. As a consequence, the search for alternative techniques for fighting micro-organisms has become one of the major issues of these last few years. In this d ...

EPFL2006

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