Concept

Early childhood education

Publications associées (35)

Butterfly effects in perceptual development: A review of the 'adaptive initial degradation' hypothesis

Human perceptual development evolves in a stereotyped fashion, with initially limited perceptual capabilities maturing over the months or years following the commencement of sensory experience into robust proficiencies. This review focuses on the functiona ...

San Diego2024

How are primary school computer science curricular reforms contributing to equity? Impact on student learning, perception of the discipline, and gender gaps

Francesco Mondada, Barbara Bruno, Laila Abdelsalam El-Hamamsy

Background Early exposure to Computer Science (CS) and Computational Thinking (CT) for all is critical to broaden participation and promote equity in the field. But how does the introduction of CS and CT into primary school curricula impact learning, perce ...

2023

The CT-cube: A framework for the design and the assessment of computational thinking activities

Francesco Mondada, Alberto Piatti, Laila Abdelsalam El-Hamamsy

Computational thinking is a fundamental competence that is being introduced in K-12 and succeeding curricula worldwide. Despite this huge effort, many computational thinking models in the literature do not explicitly take into consideration the pupils’ age ...

2022

NMR spectroscopy of a single mammalian early stage embryo

Jürgen Brugger, Giovanni Boero, Marco Grisi, Gaurasundar Marc Conley, Kyle Joel Rodriguez

The resolving power, chemical sensitivity and non-invasive nature of NMR have made it an established technique for in vivo studies of large organisms both for research and clinical applications. NMR would clearly be beneficial for analysis of entities at t ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2022

Essential role of Cp190 in physical and regulatory boundary formation

Nicolas Jean Philippe Guex, Julien Dorier, Christian Iseli

Boundaries in animal genomes delimit contact domains with enhanced internal contact frequencies and have debated functions in limiting regulatory cross-talk between domains and guiding enhancers to target promoters. Most mammalian boundaries form by stalli ...

2022

Mechanistic Understanding of Neurobehavioral Effects of Insecticides on the Larvae of Zebrafish (Danio rerio)

Sarah-Katharina Könemann

Due to conservation of neuronal functioning across phyla, molecular targets of insecticides are similar in insects and vertebrates. Insecticides thus pose a risk to aquatic vertebrates,such as fish, and potentially cause neurotoxic effects. Although these ...

EPFL2022

Analysis of Polycerate Mutants Reveals the Evolutionary Co-option of HOXD1 for Horn Patterning in Bovidae

Denis Duboule, Jozsef Zakany, Aurélie Hintermann

In the course of evolution, pecorans (i.e., higher ruminants) developed a remarkable diversity of osseous cranial appendages, collectively referred to as "headgear," which likely share the same origin and genetic basis. However, the nature and function of ...

OXFORD UNIV PRESS2021

Industry Commons: an ecosystem approach to horizontal enablers for sustainable cross-domain industrial innovation (a positioning paper)

This paper introduces the background, concept and definition of the Industry Commons. It initiates a discussion on the positioning of the Industry Commons Ecosystem (ICE) with respect to current research directions in advanced manufacturing and production ...

TAYLOR & FRANCIS LTD2021

KRAB zinc finger protein-mediated control of transposon-embedded regulatory sequences from human germline to early embryos

Alexandra Iouranova

Transposable elements (TEs), also called jumping genes, are genetic elements capable of changing their position within the genome of their host. They make up large fractions of genomes, including 45% of human DNA content, according to current estimates. S ...

EPFL2021

The Inequality of Neural Destiny: Signatures of Lifecourse Socioeconomic Conditions in Markers of Brain Tissue Myelination and Volume

Maria del Carmen Sandi Perez, Bogdan Draganski, Leyla Loued-Khenissi

Socioeconomic status (SES) plays a significant role in health and disease. At the same time, early-life conditions affect neural function and structure, suggesting the brain may be a conduit for the biological embedding of SES. Here, we investigate the neu ...

2020

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