Concept

Thyroid function tests

Publications associées (24)

Nanofibrillated cellulose composite hydrogel for the replacement of the nucleus pulposus

Dominique Pioletti, Pierre-Etienne Bourban, Ana Borges de Couraça, Fabien Duc

The swelling and compressive mechanical behavior as well as the morphology and biocompatibility of composite hydrogels based on Tween® 20 trimethacrylate (T3), N-vinyl-2-pyrrolidone (NVP) and nanofibrillated cellulose (NFC) were assessed in the present stu ...

2011

Curing Kinetics and Mechanical Properties of a Composite Hydrogel for the Replacement of the Nucleus Pulposus

Dominique Pioletti, Pierre-Etienne Bourban, Ana Borges de Couraça

A polymer material system has been developed to propose an injectable, UV and in situ curable hydrogel with properties similar to the native nucleus pulposus of intervertebral disc. Neat hydrogels based on Tween® 20 trimethacrylates (T3) and N-vinyl-2-pyrr ...

Elsevier2010

Serum Bile Acids Are Higher in Humans With Prior Gastric Bypass: Potential Contribution to Improved Glucose and Lipid Metabolism

Johan Auwerx

The multifactorial mechanisms promoting weight loss and improved metabolism following Roux-en-Y gastric bypass (GB) surgery remain incompletely understood. Recent rodent studies suggest that bile acids can mediate energy homeostasis by activating the G-pro ...

2009

Identification of a novel modulator of thyroid hormone receptor-mediated action

Jordi Duran

Diabetes is characterized by reduced thyroid function and altered myogenesis after muscle injury. Here we identify a novel component of thyroid hormone action that is repressed in diabetic rat muscle. ...

Public Library of Science2007

Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects

Johan Auwerx

CONTEXT: The type 2 iodothyronine deiodinase (D2) catalyzes the conversion of T(4) to the active form of thyroid hormone, which is a critical regulator of thermogenesis and glucose metabolism. A Thr92Ala polymorphism in the gene encoding D2 (DIO2) has been ...

2006

Lack of thyroid hormone receptor alpha1 is associated with selective alterations in behavior and hippocampal circuits

Maria del Carmen Sandi Perez, Ruth Benavides Piccione

Brain development and function are dependent on thyroid hormone (T3), which acts through nuclear hormone receptors. T3 receptors (TRs) are transcription factors that activate or suppress target gene expression in a hormone-dependent or -independent fashion ...

2003

Differential effect of thyroid hormone deficiency on the growth of calretinin-expressing neurons in rat spinal cord and dorsal root ganglia

Pierre Magistretti, Thibault Adrien Kuntzer

The development of spinal cord or dorsal root ganglia neurons expressing calretinin (CR) was studied in thyroid hormone-deficient rats. Immunocytochemical and morphometric analyses showed that the hypothyroidism induced a significant decrease in the number ...

2000

Hormonal regulation of the genes involved in lipoprotein metabolism in the rat [Contrôle hormonal des gènes impliqués dans le métabolisme lipoprotéique chez le rat]

Johan Auwerx

Despite the complex regulation of the expression of these genes, some general conclusions seem to be warranted. First, nearly all the studied genes are regulated in a tissue-specific fashion. Moreover hepatic expression seems to be more tightly controlled ...

1995

Lipoprotein lipase expression in undifferentiated hepatoma cells is regulated by progesterone and protein kinase A

Johan Auwerx

Recently, it was shown that lipoprotein lipase (LPL) was produced in neonatal but not in adult rat liver. In an attempt to further define the mechanism involved in liver LPL expression, we identified a neonatal mouse hepatoma cell line, BWTG3, capable of p ...

1992

Neonatal extinction of liver lipoprotein lipase expression

Johan Auwerx

In contrast to the complete absence of lipoprotein lipase (LPL) mRNA in adult rat liver, fetal and neonatal rat liver contain substantial amounts of LPL mRNA, which is translated in active LPL protein as can be deduced from the presence of LPL activity in ...

1992

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