Publications associées à Méthode de Lowry

Acoustofluidic large-scale mixing for enhanced microfluidic immunostaining for tissue diagnostics

Martinus Gijs, Diego Gabriel Dupouy, Muaz Salama Abdelmonem Draz

The usage of microfluidics for automated and fast immunoassays has gained a lot of interest in the last decades. This integration comes with certain challenges, like the reconciliation of laminar flow patterns of micro-scale systems with diffusion-limited ...

ROYAL SOC CHEMISTRY2023

Efficient AC electrothermal flow (ACET) on-chip for enhanced immunoassays

Martinus Gijs, Diego Gabriel Dupouy, Muaz Salama Abdelmonem Draz

Biochemical reaction rates in microfluidic systems are known to be limited by the diffusional transport of reagents, leading often to lowered sensitivity and/or longer detection times in immunoassays. Several methods, including electrically powering electr ...

ROYAL SOC CHEMISTRY2023

Investigating the composition and recruitment of the mycobacterial ImuA'-ImuB-DnaE2 mutasome

John McKinney, Neeraj Dhar, Zela Alexandria-Mae Martin

A DNA damage-inducible mutagenic gene cassette has been implicated in the emergence of drug resistance in Mycobacterium tuberculosis during anti-tuberculosis (TB) chemotherapy. However, the molecular composition and operation of the encoded 'mycobacterial ...

Cambridge2023

Linear triglycerol-based fluorosurfactants show high potential for droplet-microfluidics-based biochemical assays

Esther Amstad, Irvine Lian Hao Ong, Abhishek Kumar Singh

Fluorosurfactants have expanded the landscape of high-value biochemical assays in microfluidic droplets, but little is known about how the spatial geometries and polarity of the head group contribute to the performance of fluorosurfactants. To decouple thi ...

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Nucleosome Binding by the Lysine Specific Demethylase 1 (LSD1) Enzyme Enables Histone H3 Demethylation

Beat Fierz, Aurore Marie-France Delachat, Abhinav Dhall

The essential human enzyme lysine specific demethylase 1 (LSD1) silences genes by demethylating mono- and dimethylated lysine 4 in histone H3 (H3K4me1/2). Studies of the minimal requirements for LSD1 activity are complicated by the heterogeneity of histone ...

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An optimized and validated 384-well plate assay to test platelet function in a high-throughput screening format

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Despite significant advances in the treatment of cardiovascular diseases, antiplatelet therapies are still associated with a high risk of hemorrhage. In order to develop new drugs, methods to measure platelet function must be adapted for the high-throughpu ...

TAYLOR & FRANCIS INC2019

Microfluidic device for real-time formulation of reagents and their subsequent encapsulation into double emulsions

Esther Amstad, Sebastian Maerkl, Zoe Newell Swank, Jui-Chia Chang

Emulsion drops are often employed as picoliter-sized containers to perform screening assays. These assays usually entail the formation of drops encompassing discrete objects such as cells or microparticles and reagents to study interactions between the dif ...

Nature Publishing Group2018

Optimization of thin-film highly-compliant elastomer sensors for contractility measurement of muscle cells

Herbert Shea, Cristina Martin Olmos, Matthias Imboden, Samuel Rosset, Alexandre Poulin, Mélanie Favre, Oluwaseun Adelowo Araromi, Francesca Sorba

Test assays capable of providing quantitative characterization of the contraction of cardiac and smooth muscle cells are of great need for drug development and screening. Several methodologies have been proposed for achieving measurement of cell contractil ...

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Rapid, Sensitive and Real-Time Multiplexing Platform for the Analysis of Protein and Nucleic-Acid Biomarkers

Philippe Renaud, Nicolas Demierre, Raphaël Tornay, Lucienne Lagopoulos, David Bernasconi

We describe a multiplexing technology, named Evalution, based on novel digitally encoded microparticles in microfluidic channels. Quantitative multiplexing is becoming increasingly important for research and routine clinical diagnostics, but fast, easy-to- ...

Amer Chemical Soc2015

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Méthode de Lowry

Acoustofluidic large-scale mixing for enhanced microfluidic immunostaining for tissue diagnostics

Efficient AC electrothermal flow (ACET) on-chip for enhanced immunoassays

Investigating the composition and recruitment of the mycobacterial ImuA'-ImuB-DnaE2 mutasome

Linear triglycerol-based fluorosurfactants show high potential for droplet-microfluidics-based biochemical assays

Nucleosome Binding by the Lysine Specific Demethylase 1 (LSD1) Enzyme Enables Histone H3 Demethylation

An optimized and validated 384-well plate assay to test platelet function in a high-throughput screening format

Microfluidic device for real-time formulation of reagents and their subsequent encapsulation into double emulsions

Optimization of thin-film highly-compliant elastomer sensors for contractility measurement of muscle cells

Rapid, Sensitive and Real-Time Multiplexing Platform for the Analysis of Protein and Nucleic-Acid Biomarkers

Exploring new therapeutic strategies for Huntington's Disease

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Chattez avec Graph Search

Efficient AC electrothermal flow (ACET) on-chip for enhanced immunoassays

Investigating the composition and recruitment of the mycobacterial ImuA'-ImuB-DnaE2 mutasome

Nucleosome Binding by the Lysine Specific Demethylase 1 (LSD1) Enzyme Enables Histone H3 Demethylation

Linear triglycerol-based fluorosurfactants show high potential for droplet-microfluidics-based biochemical assays

An optimized and validated 384-well plate assay to test platelet function in a high-throughput screening format

Optimization of thin-film highly-compliant elastomer sensors for contractility measurement of muscle cells

Microfluidic device for real-time formulation of reagents and their subsequent encapsulation into double emulsions

Rapid, Sensitive and Real-Time Multiplexing Platform for the Analysis of Protein and Nucleic-Acid Biomarkers

Exploring new therapeutic strategies for Huntington's Disease