Publications associées à Sein

Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates

The breast epithelium has two major compartments, luminal and basal cells, that are established and maintained by poorly understood mechanisms. The p53 homolog, p63, is required for the formation of mammary buds, but its function in the breast after birth ...

Nature Publishing Group2010

Cyclin D1 Enhances the Response to Estrogen and Progesterone by Regulating Progesterone Receptor Expression

Cathrin Brisken

Estrogen and progesterone are the defining hormones of normal female development, and both play critical roles in breast carcinogenesis. Cyclin D1 is a breast cancer oncogene whose amplification is linked to poor prognosis in estrogen and progesterone rece ...

American Society for Microbiology2010

Bioconjugated lanthanide luminescent helicates as multilabels for lab-on-a-chip detection of cancer biomarkers

Martinus Gijs, Jean-Claude Bünzli, Anne-Sophie Chauvin, Caroline Vandevyver, Venkataragavalu Sivagnanam, Bo Song, Vanesa Fernandez Moreira, Hans-Anton Lehr

The lanthanide binuclear helicate [Eu2(LC2(CO2H))3] is coupled to avidin to yield a luminescent bioconjugate EuB1 (Q ¼ 9.3%, s(5D0) ¼ 2.17 ms). MALDI/TOF mass spectrometry confirms the covalent binding of the Eu chelate and UV-visible spectroscopy allows o ...

2010

Ultrasound Tomography with Learned Dictionaries

Martin Vetterli, Pascal Frossard, Ivana Tosic, Ivana Jovanovic

We propose a new method for imaging sound speed in breast tissue from measurements obtained by ultrasound tomography (UST) scan- ners. Given the measurements, our algorithm finds a sparse image representation in an overcomplete dictionary that is adapted t ...

2010

Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective

Cathrin Brisken

The mammary gland is a unique organ in that it undergoes most of its development after birth under the control of systemic hormones. Whereas in most other organs stem cells divide in response to local stimuli, to replace lost cells, in the mammary gland la ...

Humana Press Inc, Springer2007

An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells

Cathrin Brisken, Stéphanie Joëlle André, Maryse Fiche

INTRODUCTION: About 70% of breast cancers express oestrogen receptor alpha (ESR1/ERalpha) and are oestrogen-dependent for growth. In contrast with the highly proliferative nature of ERalpha-positive tumour cells, ERalpha-positive cells in normal breast tis ...

2007

Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism

Cathrin Brisken, Ayyakkannu Ayyanan, Maryse Fiche

Wnt and Notch signaling have long been established as strongly oncogenic in the mouse mammary gland. Aberrant expression of several Wnts and other components of this pathway in human breast carcinomas has been reported, but evidence for a causative role in ...

2006

Alveolar and lactogenic differentiation

Cathrin Brisken, Renuga Devi Rajaram

The mouse mammary gland is a complex tissue that proliferates and differentiates under the control of systemic hormones during puberty, pregnancy and lactation. Once a highly branched milk duct system has been established, during mid/late pregnancy, alveol ...

2006

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Sein

Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates

Cyclin D1 Enhances the Response to Estrogen and Progesterone by Regulating Progesterone Receptor Expression

Bioconjugated lanthanide luminescent helicates as multilabels for lab-on-a-chip detection of cancer biomarkers

Ultrasound Tomography with Learned Dictionaries

Hormonal regulation of Stat5 in the mammary gland - from signaling to morphogenesis

Gene expression profiling of the stromal reaction to invasive human breast and prostate cancer

Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective

An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells

Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism

Alveolar and lactogenic differentiation

Graph Chatbot

Chattez avec Graph Search

Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective

Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates

An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells

Gene expression profiling of the stromal reaction to invasive human breast and prostate cancer

Cyclin D1 Enhances the Response to Estrogen and Progesterone by Regulating Progesterone Receptor Expression

Alveolar and lactogenic differentiation

Hormonal regulation of Stat5 in the mammary gland - from signaling to morphogenesis

Bioconjugated lanthanide luminescent helicates as multilabels for lab-on-a-chip detection of cancer biomarkers

Ultrasound Tomography with Learned Dictionaries

Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism