Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.
AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.
Reactions of tBuP(NH2)2 with Group 13 trialkyls MR3 (M = Al, Ga, In; R = Me, tBu) were investigated in detail. According to variable-temp. (VT) NMR investigations, the reaction proceeds stepwise with the initial formation of aminophosphane adducts, which s ...
The reactivity of three cytotoxic trans-PtII complexes bearing aliph. amine ligands, with transferrin and single-stranded oligonucleotides as DNA models, was investigated by ESI-MS and the results obtained are discussed in comparison with cisplatin. Tandem ...
The binding of the ruthenium-based anticancer drug candidates KP1019, NAMI-A and RAPTA-T towards different double-stranded oligonucleotides was probed by electrospray ionisation mass spectrometry and compared with that of the widely used platinum-based che ...
During the last decades, weakly coordinating anions (WCAs) have become a field of great interest both in basic and applied chemistry, as – if compared to "normal" classical anions like Cl- or SO42- – they have a lot of unique and unusual properties, such a ...
Electrospray ionization mass spectrometry allows a rapid characterization of the adducts formed between three novel anticancer ruthenium(II)-arene PTA compds. and horse heart cytochrome c or hen egg white lysozyme. Specific information on the nature of the ...
The first solid-state structures of complexed P3N3X6 (X=halogen) are reported for X=Cl. The compounds were obtained from P3N3Cl6 and Ag[Al(OR)4] salts in CH2Cl2/CS2 solution. The very weakly coordinating anion with R=C(CF3)3 led to the salt Ag(P3N3Cl6)2+[A ...
T-BuP(NH2)2 reacts with base-stabilized group 13 tri-hydrides with adduct formation (THF-BH3), with redn. to give t-BuPH2 (Me3N-AlH3) and with elimination of H22 and formation of a metallonitridophosphinate (Me3N-GaH3). In contrast, the reaction with Cp*Ti ...
(2,6-Dichlorophenyl)trimethyl- and -triethylsilane exhibit untypical reactivity patterns toward strong bases. When treated at -100 DegC with lithium 2,2,6,6-tetramethylpiperidide, they give rise to two, with sec- or tert-butyllithium even three, different ...
HMT-C11 belongs to the family of adducts formed by the cocrystallization of N-4(CH2)(6) molecules ( hexamethylenetetramine or HMT) and aliphatic dicarboxylic acids HOOC(CH2)(n-2)COOH with 5 less than or equal to n less than or equal to 13 (Cn). The adducts ...
The invention relates to a novel class of ligands, complexes comprising such ligands and a metal ion, and adducts of these metal complexes and a macromolecule. Pharmaceutical compositions and methods of making and using the ligand-metal complexes are also ...