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The ability to determine the location and relative strength of all transcription-factor binding sites in a genome is important both for a comprehensive understanding of gene regulation and for effective promoter engineering in biotechnological applications ...
Even if many research projects in population genetics and conservation biology collect a quantity of spatially located biological samples, and despite its present predominance in Science and its direct application to concerns of public society (health, foo ...
The complex secondary metabolite anachelin, isolated from the freshwater cyanobacterium Anabaena cylindrica, is believed to act as siderophore, facilitating iron uptake. Its structure is characterized by a fascinating blend of polyketide, peptide, and alka ...
The aim of this contribution is to review the application of thermodynamics to live cultures of microbial and other cells and to explore to what extent this may be put to practical use. A major focus is on energy dissipation effects in industrially relevan ...
Biotechnology is an area of great innovations that promises to have deep impact on everyday life thanks to profound changes in biology, medicine, and health care. This article will span from the description of the biochemical principles of molecular biolog ...
The paper discusses the recent achievements in the development of chips with integrated sensing of biomolecules. In particular, it focuses on integrated sensing electrodes on silicon and presents innovative solutions for the enhanced robustness of the elec ...
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The construction of enzymatic microsensors based on semiconductor technology and photo-curable membranes is reported in this work. A planar three-microelectrode cell and a pH-sensitive Ion Selective Field-Effect Transistor (ISFET) with Si3N4 membrane have ...
With a growing number of cell-based biotechnological applications, there is a need for particle separation systems capable of multiparameter separations at high purity and throughput, beyond what is presently offered by traditional methods including fluore ...
This review sums up the activity in the field of in situ product removal in whole cell bioprocesses over the last 20 yr. It gives a complete summary of ISPR operations with microbial cells and cites a series of interesting ISPR applications in plant and an ...
A rapid biological method for the determination of the bioavailability of naphthalene was developed and its value as an alternative to extraction-based chemical approaches demonstrated. Genetically engineered whole-cell biosensors are used to determine bio ...