Concept
Nucleic acid hybridization
Publications associées (74)
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Determining the spatial organization and morphological characteristics of molecularly defined cell types is a major bottleneck for characterizing the architecture underpinning brain function. We developed Expansion Assisted Iterative Fluorescence In Situ H ...
CELL PRESS2021Improvement of breast cancer diagnosis through microfluidics
In breast cancer, 15-20% of cases are reported with overexpression of human epidermal growth factor receptor 2 (HER2) that causes rapid cancer progression and poor prognosis. Fortunately, HER2-targeted therapy using specific antibodies such as Trastuzumab ...
EPFL2018Chromosomal contacts connect loci associated with autism, BMI and head circumference phenotypes
Bart Deplancke, Marion Leleu, Nele Gheldof, Loyse Hippolyte
Copy number variants (CNVs) are major contributors to genomic imbalance disorders. Phenotyping of 137 unrelated deletion and reciprocal duplication carriers of the distal 16p11.2 220 kb BP2-BP3 interval showed that these rearrangements are associated with ...
Springer Nature2017