Concept

Monocyte

Publications associées (89)

Effect of microcapsule composition and short-term immunosuppression on intraportal biocompatibility

Jutta Christine Wandrey, David Hunkeler, Dianelys Sainz Vidal

With higher nutrient and oxygen supply and close contact to blood, the portal vein is a possible alternative to the peritoneal cavity for transplantation of encapsulated cells. Data regarding intraportal biocompatibility of microcapsules are lacking. Micro ...

2005

PPARalpha downregulates airway inflammation induced by lipopolysaccharide in the mouse

Johan Auwerx

BACKGROUND: Inflammation is a hallmark of acute lung injury and chronic airway diseases. In chronic airway diseases, it is associated with profound tissue remodeling. Peroxisome proliferator-activated receptor-alpha (PPARalpha) is a ligand-activated transc ...

2005

Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors

Michele De Palma

Bone marrow-derived cells contribute to tumor angiogenesis. Here, we demonstrate that monocytes expressing the Tie2 receptor (Tie2-expressing monocytes [TEMs]) (1) are a distinct hematopoietic lineage of proangiogenic cells, (2) are selectively recruited t ...

Elsevier2005

Modulation of the host immune response by a transient intracellular stage of Mycobacterium ulcerans: the contribution of endogenous mycolactone toxin

Stewart Cole

Mycobacterium ulcerans (Mu), the aetiological agent of Buruli ulcer, is an extracellular pathogen producing the macrolide toxin mycolactone. Using a mouse model of intradermal infection, we found that Mu was initially captured by phagocytes and transported ...

2005

Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation

Nicola Harris

Persistence is a hallmark of infection by viruses such as HIV, hepatitis B virus, hepatitis C virus and LCMV. In the case of LCMV, persistence may often be associated with exhaustion of CD8(+) T cells. We demonstrate here that persistent antigen suppressed ...

2005

Dielectric spectroscopy in a microfabricated flow cytometer

Shady Didier Gawad

In this thesis, a new microfabricated flow cytometer for single cell discrimination based on dielectric spectroscopy is presented. Integrated tools for rapid in-flow cell handling are also demonstrated. Signal amplification and analysis as well as the chip ...

EPFL2004

New insights into catalytic hydrogenation by phosphido-substituted triruthenium clusters: confirmation of intact cluster catalysis by parahydrogen NMR

Paul Joseph Dyson

The phosphido-substituted triruthenium cluster Ru-3(CO)(9)(mu-H)(mu-PPh2) is shown to react with H-2 to form the trihydride cluster Ru-3(CO)(9)(H)(mu-H)(2)(mu-PPh2), which undergoes a number of re-arrangement reactions on heating to yield other phosphido-s ...

2004

The Listeria monocytogenes lemA gene product is not required for intracellular infection or to activate fMIGWII-specific T cells

Clearance of the intracellular bacterial pathogen Listeria monocytogenes requires antigen-specific CD8(+) T cells. Recently it was shown that activation of class Ib major histocompatibility complex (MHC)-restricted CD8(+) T cells alone is sufficient for im ...

American Society for Microbiology2003

Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus

Freddy Radtke, Anne Wilson

We have recently reported that Notch 1, a member of the Notch multigene family, is essential for the development of murine T cells. Using a mouse model in which Notch 1 is inactivated in bone marrow (BM) precursors we have shown that B cells instead of T c ...

2001

Protein-mediated macrophage adhesion and activation on biomaterials: a model for modulating cell behavior

Jeffrey Alan Hubbell

The elucidation of proteins involved in biomaterial-modulated macrophage behavior is crit. for the improvement of material performance and the initial exploration of material design capable of manipulating macrophage function for tissue engineering. Severa ...

1999

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