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Fusion proteins containing a first domain and a second domain, where the first domain contains a crosslinkable substrate domain and the second domain contains a fibrinolysis inhibitor, are provided. In a preferred embodiment, the fibrinolysis inhibitor is ...
In the current Internet, there is no clean way for affected parties to react to poor forwarding performance: to detect and assess Service Level Agreement (SLA) violations by a contractual partner, a domain must resort to ad-hoc monitoring using probes. Ins ...
The spatial domain of Molecular Dynamics simulations is usually a regular box that be easily divided in subdomains for parallel processing. Recent efforts aimed at simulating complex biological systems, like the blood flow inside arteries, require the exec ...
A number of bacterial virulence factors have been observed to adopt structures similar to that of aerolysin, the principal toxin of Aeromonas species. However, a comprehensive description of architecture and structure of the aerolysin-like superfamily has ...
Nowadays, hardware devices are meant to host the execution of many complex, multi-core applications, whose functional and non-functional requirements vary according to the specific working domain. In this work, we propose a design methodology that combines ...
Institute of Electrical and Electronics Engineers2011
SARA, an early endosomal protein, plays a key role in TGFβ signalling, as it presents SMAD2 and SMAD3 for phosphorylation by the activated TGFβ receptors. Here, we show that ERBIN is a new SARA-interacting protein that can be recruited by SARA to early end ...
In the current Internet, there is no clean way for affected parties to react to poor forwarding performance: to detect and assess Service Level Agreement (SLA) violations by a contractual partner, a domain must resort to ad-hoc monitoring using probes. Ins ...
Network tomography establishes linear relationships between the characteristics of individual links and those of end-to-end paths. It has been proved that these relationships can be used to infer the characteristics of links from end-to-end measurements, p ...
Hidden information is a critical issue for the successful delivery of services in grid systems. It arises when the agents (hardware and software resources) employed to serve a task belong to multiple administrative domains, thus rendering monitoring of rem ...
The explosive growth of online social networks (OSNs) and their wide popularity suggest the impact of OSNs on today's Internet. At the same time, concentration of vast amount of personal information within a single administrative domain causes critical pri ...