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Publications associées (22)

Dietary Fiber Is Essential to Maintain Intestinal Size, L-Cell Secretion, and Intestinal Integrity in Mice

Dietary fiber has been linked to improved gut health, yet the mechanisms behind this association remain poorly understood. One proposed mechanism is through its influence on the secretion of gut hormones, including glucagon-like peptide-1 (GLP-1) and gluca ...

FRONTIERS MEDIA SA2021

A new elementary proof of the Prime Number Theorem

Florian Karl Richter

Let

\Omega(n)

denote the number of prime factors of

n

. We show that for any bounded

f\colon\mathbb{N}\to\mathbb{C}

one has [ \frac{1}{N}\sum_{n=1}^N, f(\Omega(n)+1)=\frac{1}{N}\sum_{n=1}^N, f(\Omega(n))+\mathrm{o}_{N\to\infty}(1). ] This yields a ...

2021

Drone-ready robotic gripper powered by shape memory alloys

Gabriel Maquignaz

For this project, the goal is to design a flexure-based gripper mechanism actuated by a Shape-Memory Alloy spring (SMA) and to be mounted on a drone. While being complex to control precisely and having a very small bandwith, SMA actuators show a formidable ...

2021

New and improved methods for integrated models of metabolism and gene expression

Pierre Guy Rémy Salvy

The beginning of the 21st century was marked by the advent of disruptive technologies, which ushered an era of groundbreaking advances in fundamental sciences, carried by the great pace at which computational capabilities spread and evolved. But the new ce ...

EPFL2021

Neutrophils suppress tumor-infiltrating T cells in colon cancer via matrix metalloproteinase-mediated activation of TGF beta

Freddy Radtke, George Coukos, Nadine Fournier, Mauro Delorenzi, Marc-Olivier Sauvain, Amber Dawn Bowler, Markus Germann

High T-cell infiltration in colorectal cancer (CRC) correlates with a favorable disease outcome and immunotherapy response. This, however, is only observed in a small subset of CRC patients. A better understanding of the factors influencing tumor T-cell re ...

WILEY2020

NCoR1 Protects Mice From Dextran Sodium Sulfate Induced Colitis by Guarding Colonic Crypt Cells From Luminal Insult

Johan Auwerx

BACKGROUND & AIMS: Colonic stem cells are essential for producing the mucosal lining, which in turn protects stem cells from insult by luminal factors. Discovery of genetic and biochemical events that control stem cell proliferation and differentiation can ...

2020

Micellization behavior of bile salt with pluronic (F-127) and synthesis of silver nanoparticles in a mixed system

Mohammad Khaja Nazeeruddin

The sequestrant is a substance used to cure bile salt diarrhea. They bind to bile salts by hydrophobic and electrostatic forces to stop them from contact with colon mucosa. The block copolymer could be used as bile salt binding agents. Herein, the physicoc ...

WILEY2019

Classification of Healthy and Cancer States of Colon Epithelial Tissues Using Opto-magnetic Imaging Spectroscopy

Marko Baros, Ivan Dimitrijevic

Colorectal carcinoma (CRC) as a major health problem in industrialized countries is highly preventable and can be successfully treated in the early stages. However, incidence and mortality of CRC has increased over the last two decades. The reason could be ...

2019

On null hypotheses in survival analysis

Mats Julius Stensrud, Pal Christie Ryalen

The conventional nonparametric tests in survival analysis, such as the log-rank test, assess the null hypothesis that the hazards are equal at all times. However, hazards are hard to interpret causally, and other null hypotheses are more relevant in many s ...

2019

SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150

Paloma Ordonez Moran

SPROUTY-2 (SPRY2) is a modulator of tyrosine kinase receptor signaling with receptor-and cell type-dependent inhibitory or enhancing effects. Studies on the action of SPRY2 in major cancers are conflicting and its role remains unclear. Here we have dissect ...

Nature Publishing Group2016

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A new elementary proof of the Prime Number Theorem

Florian Karl Richter

Let

\Omega(n)

denote the number of prime factors of

n

. We show that for any bounded

f\colon\mathbb{N}\to\mathbb{C}

one has [ \frac{1}{N}\sum_{n=1}^N, f(\Omega(n)+1)=\frac{1}{N}\sum_{n=1}^N, f(\Omega(n))+\mathrm{o}_{N\to\infty}(1). ] This yields a ...

2021