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NOTCH1 is a well-established lineage specifier for T cells and among the most frequently mutated genes throughout all subclasses of T cell acute lymphoblastic leukemia (T-ALL). How oncogenic NOTCH1 signaling launches a leukemia-prone chromatin landscape du ...
The main objective of this thesis is to improve the understanding of the position and characteristics of karst conduits within a rock massif. Such a characterisation is an important issue in civil engineering and in hydrogeology. Today in practice dissolut ...
Aim A current debate in microbial biogeography contrasts two views concerning the distribution of free-living microorganisms. The first view assumes a ubiquitous distribution, while the second view assumes that at least some species have limited geographic ...
To date, little is known about the role of spring waters with respect to authigenic carbonate precipitation in a shallow lacustrine setting. Lake Ohrid, located in Southeastern Europe, is a large lake fed to over 50% by karstic springs of which half enter ...