Concept
Transfusion de plaquettes
Publications associées (13)
An optimized and validated 384-well plate assay to test platelet function in a high-throughput screening format
Nikolaos Stergiopoulos, Olivier Burri, Marc Chambon, Julien Bortoli Chapalay, Fabiana Pereira Da Costa Fraga, Augusto Martins Lima, Maiia Bragina
Despite significant advances in the treatment of cardiovascular diseases, antiplatelet therapies are still associated with a high risk of hemorrhage. In order to develop new drugs, methods to measure platelet function must be adapted for the high-throughpu ...
TAYLOR & FRANCIS INC2019Adamts18 deletion results in distinct developmental defects and provides a model for congenital disorders of lens, lung, and female reproductive tract development
Cathrin Brisken, Marian Caikovski, Alessandra Piersigilli, Dalya Ataca, Yakir Guri
The ADAMTS family comprises 19 secreted metalloproteinases that cleave extracellular matrix components and have diverse functions in numerous disease and physiological contexts. A number of them remain 'orphan' proteases, among them ADAMTS18, which has bee ...
Company Of Biologists Ltd2016Textured BaTiO3 by templated grain growth and electrophoretic deposition
[001]-Oriented barium titanate (BaTiO3) ceramics were prepared by templated grain growth using [001]-oriented plate-like template BaTiO3 particles, synthesized via the molten salt method. Platelets synthesized in a 2-step or 3-step molten salt were used in ...
Springer Verlag2015Bioactive Lipids Lysophosphatidic Acid and Sphingosine 1-Phosphate Mediate Breast Cancer Cell Biological Functions Through Distinct Mechanisms
Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) are structurally related bioactive lipids with growth factor-like activities. LPA and SIP are naturally produced in vivo by blood platelets upon platelet aggregation and at least in vitro by fib ...
2009