Concept
Structural alignment
Personnes associées (53)
Henning Paul-Julius Stahlberg
Positions:
Since 2020 Prof. Physics, IPHYS, SB, EPFL, Switzerland 2009 – 2021 Prof. Structural Biology, Biozentrum, University Basel, Switzerland
2009 – 2010 Adj. Assoc. Prof. Molecular & Cellular Biology, UC Davis, CA, USA
2007 – 2009 Assoc. Prof. Molecular & Cellular Biology, UC Davis, CA, USA
2003 – 2007 Assist. Prof. Molecular & Cellular Biology, UC Davis, CA, USA
Education: 2002 Habilitation, Biozentrum, University Basel, Switzerland 1997 – 2003 Postdoctoral Fellow, Biozentrum, University Basel, Switzerland 1992 – 1997 PhD Student, EPFL, Lausanne, Switzerland 1990 – 1991 Diploma Thesis in Solid State Physics, TU Berlin, Germany 1987 – 1993 Study of Physics, TU Berlin, Germany Selected Awards & Honors: 2009 W.M.Keck Award 2004 CAREER award, NSF, USA 2002 Habilitation, University Basel, Switzerland Selected Memberships: 2008 – 2013 Chancellor’s Fellow Award, UC Davis, CA, USA 2004 – 2009 Faculty of 1000 Since 1992 Swiss Society for Optics and Microscopy (SSOM)
Matteo Dal Peraro
Matteo Dal Peraro graduated in Physics at the University of Padua in 2000. He obtained his Ph.D. in Biophysics at the International School for Advanced Studies (SISSA, Trieste) in 2004. He then received postdoctoral training at the University of Pennsylvania (Philadelphia) under the guidance of Prof. M. L. Klein. He was nominated Tenure Track Assistant Professor at the EPFL School of Life Sciences in late 2007.
His research at the Laboratory for Biomolecular Modeling (LBM), within the Interfaculty Institute of Bioengineering (IBI), focuses on the multiscale modeling of large macromolecular systems.
Ursula Röthlisberger
U. Röthlisberger was born in Solothurn (Switzerland). In 1988 she made her diploma in Physical Chemistry in the group of Prof. Ernst Schumacher at the University of Berne (Switzerland). Her Ph.D. thesis was done in collaboration with Dr. Wanda Andreoni at the IBM Zurich Research Laboratory in Rüschlikon. After finishing her Ph.D in 1991 she spent some time as a postdoctoral research assistant at the IBM Research Lab. From 1992-1995 she was a postdoctoral research assistant in the group of Prof. Michael L. Klein at the University of Pennsylvania in Philadelphia (USA). In 1994 she was awarded an advanced researcher fellowship (Profil 2) from the Swiss National Science Foundation. Before starting her Profile 2-fellowship she spent another year as postdoctoral research assistant in the group of Prof. Michele Parrinello at the Max-Planck-Institute for Solid State Physics in Stuttgart, Germany. In 1996 she moved as Profile 2-fellow to the ETH in Zurich, hosted by the group of Prof. Wilfred F. van Gunsteren. In 1997 she became Assistant Professor of Computer-Aided Inorganic Chemistry at the ETH Zurich.
Stewart Cole
Professor Stewart Cole is an international authority in bacterial molecular-genetics and genomics. He has made outstanding contributions in several fields including: bacterial anaerobic electron transport; genome analysis of retroviruses and papillomaviruses; antibiotic resistance mechanisms; and the molecular microbiology of toxigenic clostridia. His studies on isoniazid and multidrug resistance in Mycobacterium tuberculosis, together with his pioneering work on the pathogenicity, evolution and genomics of the tubercle and leprosy bacilli, have made him an undisputed leader in the field of mycobacterial research. The findings of his research are of direct relevance to public health and disease-control in both the developing world and the industrialised nations. He has published over 250 scientific papers and review articles, and holds many patents.
Ian Smith
PhD Université de Cambridge, 1982 Interêts 1 Contrôle actif de la forme des structures pour améliorer leur aptitude au service et leur déploiement 2 Structures biomimétiques (apprentissage, auto-diagnostic, auto-réparation) 3 Gestion de l'infrastructure par l'identification structurale 4 Applications avancées de l'informatique Plus de détails, voir https://www.epfl.ch/labs/imac/fr/recherche/smith_ian_fr/
Alfredo Pasquarello
Alfredo Pasquarello effectue ses études en physique à l'Ecole normale supérieure de Pise et à l'Université de Pise et obtient leurs diplômes respectifs en 1986. Il obtient le titre de Docteur ès sciences à l'EPFL en 1991 avec une thèse portant sur les transitions à plusieurs photons dans les solides. Ensuite, il effectue des recherches post-doctorales aux Laboratoires Bell (Murray Hill, New Jersey) sur les propriétés magnétiques des fullerènes de carbone. En 1993, il rejoint l'Institut romand de recherche numérique en physique des matériaux (IRRMA), où sa recherche porte sur des méthodes de simulation ab initio. En 1998, le Prix Latsis de l'EPFL lui est decerné pour son travail de recherche portant sur les matériaux à base de silice désordonnée. Bénéficiant de plusieurs subsides du Fonds National, il constitue ensuite sa propre équipe de recherche à l'IRRMA. En juillet 2003, il est nommé Professeur en Physique théorique de la matière condensée à l'EPFL. Actuellement, il dirige la Chaire de simulation à l'échelle atomique.
Yves Weinand
Biography
Architect and civil engineer, Prof. Dr. Yves Weinand is one of the most recognised researchers in the field of contemporary wood construction. Founder of the Bureau d'Etude Weinand, he has, since 1996, designed and worked on many emblematic wooden buildings, such as the Saint Loup Chapel, the new Vaudois Parliament or, more recently, the Timber Pavilion of Vidy in Lausanne. His fundamental research questions the technical and static possibilities of wooden materials. The interdisciplinary exploration carried out at the EPFL's Laboratory for Timber Constructions (Ibois), of which he is director, concerns wood in all its aspects, from round wood to manufactured wood. The recent research carried out at Ibois on free structures with wood-wood connections (without screw nor glue) has been the subject of several technological transfers, and stands as tangible proof of new possibilities for wood construction. Yves Weinand is currently working on a large-scale project for a hall for the head office of a joinery in Luxembourg, consisting of a succession of arches with spans of 22.5 to 53.7m, entirely assembled in wood ). Through new innovative approaches, the ambition of his research is to develop a new generation of renewable and ecological wooden construction.He is regularly invited to present his work at international symposia on timber construction.
Fields of expertise Architectural designTimber structuresDigital FabricationRobotic AssemblyStructural Wood mechanicsIntegrally Attached Timber plate structures
Distinctions 2012 Grand Prix d'Architecture de Wallonie 2014 Best Paper Award, Advances in Architectural Geometry conference. (IBOIS team) 2017 Medal for Research and Technique by the Academy of Architecture. 2018 Mention Régionale, Prix Lignum for the Timber Pavilion of Vidy-Lausanne 2019 "Disctinction Bois 2019" for the Nouveau Parlement vaudois.2019 Grand Prix d'Architecture de Wallonie____________________________________________________________________________ Selected publications Les Cahiers de l'Ibois/ Ibois Notebooks 1, F. Fromonot, S. Berthier, Y. Rocher, publication directors: Y. Weinand et C. Catsaros, 2020 EPFL Press Le Pavillon en bois du Théâtre de Vidy, under the direction of Yves Weinand; V. Baudriller, J. Gamerro, M. Jaccard, C. Robeller; 2017, PPURAdvanced Timber Structures - Architectural Designs and Digital Dimensioning, Y. Weinand, 2017, Birkhaüser, publié en trois langues (french : Structures Innovantes en Bois (2016); german : Neue Holztragwerke - Architektonische Entwürfe und digitale Bemessung (2017)Grubenmann Project / Projekt Grubenmann, Y. Weinand, 2016, Stiftung Grubenmann-SammlungTimber Project: Nouvelles formes d’architectures en bois, Y. Weinand, 2010, PPURArchitexto, Y. Weinand and D. Darcis, 2009, Editions Fourre-Tout, LiègeLe bois soudé, B. Stamm and Y. Weinand, 2004, Architecture Bois & DépendanceNew Modeling - projeter ensemble, Y. Weinand, 2003, PPUR
Fields of expertise Architectural designTimber structuresDigital FabricationRobotic AssemblyStructural Wood mechanicsIntegrally Attached Timber plate structures
Distinctions 2012 Grand Prix d'Architecture de Wallonie 2014 Best Paper Award, Advances in Architectural Geometry conference. (IBOIS team) 2017 Medal for Research and Technique by the Academy of Architecture. 2018 Mention Régionale, Prix Lignum for the Timber Pavilion of Vidy-Lausanne 2019 "Disctinction Bois 2019" for the Nouveau Parlement vaudois.2019 Grand Prix d'Architecture de Wallonie____________________________________________________________________________ Selected publications Les Cahiers de l'Ibois/ Ibois Notebooks 1, F. Fromonot, S. Berthier, Y. Rocher, publication directors: Y. Weinand et C. Catsaros, 2020 EPFL Press Le Pavillon en bois du Théâtre de Vidy, under the direction of Yves Weinand; V. Baudriller, J. Gamerro, M. Jaccard, C. Robeller; 2017, PPURAdvanced Timber Structures - Architectural Designs and Digital Dimensioning, Y. Weinand, 2017, Birkhaüser, publié en trois langues (french : Structures Innovantes en Bois (2016); german : Neue Holztragwerke - Architektonische Entwürfe und digitale Bemessung (2017)Grubenmann Project / Projekt Grubenmann, Y. Weinand, 2016, Stiftung Grubenmann-SammlungTimber Project: Nouvelles formes d’architectures en bois, Y. Weinand, 2010, PPURArchitexto, Y. Weinand and D. Darcis, 2009, Editions Fourre-Tout, LiègeLe bois soudé, B. Stamm and Y. Weinand, 2004, Architecture Bois & DépendanceNew Modeling - projeter ensemble, Y. Weinand, 2003, PPUR
Hilal Lashuel
2012-2013 Visiting Professor, Standford University. Stanford School of Medicine
2011- Associate Professor of Life Sciences-Brain Mind Institute-EPFL
Dir. Laboratory of Chemical Biology of Neurodegeneration
2005-2011 Assistant Professor of Life Sciences-Brain Mind Institute-EPFL
Dir. Laboratory of Molecular Neurobiology and Neuroproteomics
2005-2008 Director- EPFL Proteomic Core Facility
2002-2004 Instructor of Neurology- Harvard Medical School and Brigham and Women's
Hospital
2001-2002 Sabbatical Fellow- Laboratory for Drug Discovery in Neurodegeneration
Harvard Medical School,
2001-2002 Post-doctoral Fellow- Center for Neurologic Diseases
Harvard Medical School and Brigham and Women's Hospital
Advisor- Prof. Peter T. Lansbury
2000-2001 Research Scientist, The Picower Institute for Medical Research, Great Neck
New York
1994-2000 PhD Student; Texas A&M University and the Scripps Research Institute
Advisor- Prof. Jeffery W. Kelly
1990-1994 B.S. City University of New York, Brooklyn College
Dr. Hilal A. Lashuel received his B.Sc. degree in chemistry from the City University of New York in 1994 and completed his doctoral studies at Texas A&M University and the Scripps Research Institute in 2000. After obtaining his doctoral degree, he became a research fellow at the Picower Institute for Medical Research in Long Island New York. In 2001, he moved to Harvard Medical School and the Brigham and Women's Hospital as a research fellow in the Center for Neurologic Diseases and was later promoted to an instructor in neurology at Harvard Medical School. During his tenure (2001-2004) at Harvard Medical School his work focused on understanding the mechanisms of protein misfolding and fibrillogenesis and the role of these processes in the pathogenesis of Parkinson's and Alzheimer's disease. In 2005 Dr. Lashuel moved Switzerland to join the Brain Mind Institute at the Swiss Federal Institute of Technology Lausanne as a tenure-track assistant professor in neurosciences. Currently, Dr. Lashuel is an associate professor of life sciences and the director of the laboratory of molecular and chemical biology of neurodegeneration. (http://lashuel-lab.epfl.ch/).
Research efforts in the Lashuels laboratory focus on understanding the molecular mechanisms of neurodegeneration and developing novel strategies to diagnose and treat neurodegenerative diseases such as Alzheimers and Parkinsons disease. Research in the Lashuel lab is funded by several international funding agencies and foundations, including the Swiss National Science Foundation, European FP7 program (Marie Curie and ERC grants), Human Science Frontiers, Strauss Foundation, Cure the Huntingtons disease foundation and Michael J Fox foundation and is supported by collaborations with pharmaceutical and biotech companies (http://lashuel-lab.epfl.ch/page-50538-en.html), Nestle, Merck-Serono, AC Immune and Johnson and Johnson.
Dr. Lashuels research has resulted in the characterization of novel quaternary structure intermediates on the amyloid pathway, identification of potential therapeutic targets, and new hypotheses concerning the mechanisms of pathogenesis in Alzheimers disease, Parkinsons disease and related disorders. Dr. Lashuel scientific contribution to this field includes i) more than100 publications in major peer reviewed journals including Nature journals, Cell, PNAS, JBC, J. Neuroscience JACS, and Angewandtie Chemie; ii) three patents on novel strategies for preventing protein aggregation and treating autoimmune and inflammatory diseases; iii) more than 150 invited lectures since 2002 and more than 5500 citations (7800 citation-Google Scholar) since 1996. Dr. Lashuel has received several pre-doctoral and post-doctoral awards and fellowships and was the recipient of two prestigious awards given to young investigators; Human Science Frontiers young investigator research award and the European Research Council (ERC) starting independent researcher grant and the ERC proof of concept award (2013) These awards provide more than $2.5 Million to Dr. Lashuel to translate some of his ideas and projects into novel strategies for diagnosing and treating neurodegenerative diseases such as Alzheimers and Parkinsons disease. Dr. Lashuel has chaired and co-organized several international conferences and serves as an academic editor for PLoS ONE, an associate editor for frontiers of molecular neuroscience, member of the Editorial advisory board of ChemBioChem and ad hoc reviewer for several international scientific journals and funding agencies.