Concept
Benzodiazépine
Publications associées (34)
Trifluoromethoxy Substituted Anilines: Metalation as the Key Step for Structural Elaboration
Trifluoromethoxy-substituted anilines undergo hydrogen/lithium permutation ("metalation") with optional site selectivity depending on the N-protective group employed. N-tert-Butoxycarbonyl-2- and -4-(trifluoromethoxy)aniline react with tert-BuLi at the n ...
2003Multiresolution Imaging of In Vivo Ligand-Receptor Interactions
The aim of this study is to obtain voxel-by-voxel images of binding parameters between [11C]-Flumazenil and benzodiazepine receptors using positron emission tomography (PET). We estimate five local parameters (k1, k2, B'max, kon/VR, koff) by fitting a thre ...
SPIE2001Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients
Neuronal growth factors hold promise for providing therapeutic benefits in various neurological disorders. As a means of ensuring adequate central nervous system delivery of growth factors and minimizing significant adverse side effects associated with sys ...
1996