Concept
Specialty drugs in the United States
Publications associées (5)
Multiomic analysis of HER2-enriched and AR-positive breast carcinoma with apocrine differentiation and an oligometastatic course: a case report
Breast carcinoma is the most prevalent cancer among women globally. It has variable clinical courses depending on the stage and clinical-biological features. This case report describes a 56-year-old female with invasive breast cancer without estrogen or pr ...
FRONTIERS MEDIA SA2023Current Trends in Multidrug Optimization: An Alley of Future Successful Treatment of Complex Disorders
The identification of effective and long-lasting cancer therapies still remains elusive, partially due to patient and tumor heterogeneity, acquired drug resistance, and single-drug dose-limiting toxicities. The use of drug combinations may help to overcome ...
Sage Publications Inc2017Optimization of drug combinations using Feedback System Control
Paul Joseph Dyson, Hubert van den Bergh, Patrycja Nowak-Sliwinska
We describe a protocol for the discovery of synergistic drug combinations for the treatment of disease. Synergistic drug combinations lead to the use of drugs at lower doses, which reduces side effects and can potentially lead to reduced drug resistance, w ...
Nature Publishing Group2016A streamlined search technology for identification of synergistic drug combinations
Paul Joseph Dyson, Hubert van den Bergh, Patrycja Nowak-Sliwinska
A major key to improvement of cancer therapy is the combination of drugs. Mixing drugs that already exist on the market may offer an attractive alternative. Here we report on a new model-based streamlined feedback system control (s-FSC) method, based on a ...
Nature Publishing Group2015Bioluminescent sensor proteins for point-of-care therapeutic drug monitoring
To ensure efficacy but avoid toxicity, many drugs require monitoring of their concentrations in the patient’s blood during therapy. Currently, therapeutic drug monitoring (TDM) is done in diagnostic laboratories that need trained personnel and expensive in ...
EPFL2013