Concept

Aristotle's biology

Publications associées (22)

Correlating cryo-super resolution radial fluctuations and dual-axis cryo-scanning transmission electron tomography to bridge the light-electron resolution gap

Visualization of organelles and their interactions with other features in the native cell remains a challenge in modern biology. We have introduced cryo-scanning transmission electron tomography (CSTET), which can ac-cess 3D volumes on the scale of 1 micro ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2023

Pedestrian Crossings as a Means of Reducing Conflicts between Cyclists and Pedestrians in Shared Spaces

Evangelos Paschalidis

One significant and simultaneously interesting problem in urban mobility has to do with the study of shared spaces where various categories of users coexist and act together. This paper aims to examine the behavior and preferences of pedestrians and cyclis ...

2023

Il demone dell'analogia: Ovvero affinità e divergenze fra il compagno aristotele e noi

Nicola Braghieri

This laconic discourse uses the Aristotelian authority to define the role of the analogical procedure in the government of the architectural composition. Respecting its ambiguous balance between mathematical method and attitude of the imagination, analogy ...

2021

Multi-omics reveals abundant mitochondrial genomic and circadian expression variation in the Drosophila Genetic Reference Panel

Maria Litovchenko

Modern biology rapidly generates a wealth of data,which can only be analysed computationally.Despite the variety of available data types,most of them aim to provide an answer to one question: how does genotypic diversity translates into phenotypes? This qu ...

EPFL2020

ASAP 2020 update: an open, scalable and interactive web-based portal for (single-cell) omics analyses

Bart Deplancke, Vincent Roland Julien Gardeux, Maria Litovchenko

Single-cell omics enables researchers to dissect biological systems at a resolution that was unthinkable just 10 years ago. However, this analytical revolution also triggered new demands in 'big data' management, forcing researchers to stay up to speed wit ...

OXFORD UNIV PRESS2020

Characterization of Protein-Membrane Interfaces through a Synergistic Computational-Experimental Approach

Alessio Prunotto

The characterization of biological interfaces is widely recognized as one of the main challenges for modern biology. In particular, biological membranes are nowadays known to be an active environment that allows membrane proteins to perform their work and ...

EPFL2020

Automated phenotyping of Caenorhabditis elegans embryos with a high-throughput-screening microfluidic platform

Martinus Gijs, Matteo Cornaglia, Raphaël Etienne Jean Trouillon, Hüseyin Baris Atakan, Tunç Alkanat

The nematode Caenorhabditis elegans has been extensively used as a model multicellular organism to study the influence of osmotic stress conditions and the toxicity of chemical compounds on developmental and motility-associated phenotypes. However, the sev ...

2020

Microfluidics as an Emerging Precision Tool in Developmental Biology

Christoph Merten

Microfluidics has become a precision tool in modern biology. It enables omics data to be obtained from individual cells, as compared to averaged signals from cell populations, and it allows manipulation of biological specimens in entirely new ways. Cells a ...

2019

Progress and potential in organoid research

Matthias Lütolf, Giuliana Rossi, Andrea Manfrin

Tissue and organ biology are very challenging to study in mammals, and progress can be hindered, particularly in humans, by sample accessibility and ethical concerns. However, advances in stem cell culture have made it possible to derive in vitro 3D tissue ...

2018

Efficient inference for genetic association studies with multiple outcomes

Anthony Christopher Davison, Jörg Hager, Hélène Ruffieux

Combined inference for heterogeneous high-dimensional data is critical in modern biology, where clinical and various kinds of molecular data may be available from a single study. Classical genetic association studies regress a single clinical outcome on ma ...

Oxford University Press2017

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