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Publications associées (146)

Capture system adapted to capture orbital objects, in particular for deorbiting purposes

Pierre-Alain Mäusli, Muriel Richard, Michaël Pellet

There is described a capture system (100) adapted to capture orbital objects (2000), in particular for deorbiting purposes. The capture system (110) comprises (i) a deployable capture structure (110) designed to be deployable between a standby configuratio ...

2020

Structural and DNA binding properties of mycobacterial integration host factor mIHF

Stewart Cole, David Lyndon Emsley, Giovanni Dietler, Luciano Andres Abriata, Nina Theres Odermatt, Moreno Lelli, Jérémie Piton, Aleksandre Japaridze, Rajkumar Singh

In bacteria, nucleoid associated proteins (NAPs) take part in active chromosome organization by supercoil management, three-dimensional DNA looping and direct transcriptional control. Mycobacterial integration host factor (mIHF, rv1388) is a NAP restricted ...

2020

Crosslinking Allosteric Sites on the Nucleosome Core Particle

Lucinda Kate Batchelor

Designing compounds that bind to the acidic patch of the nucleosome core particle (NCP) is an emerging therapeutic approach that can inhibit the binding of key chromatin factors. Pretreatment of human ovarian carcinoma, A2780, cells with RAPTA-T, an antime ...

EPFL2019

Atomic Motif Recognition in (Bio)Polymers: Benchmarks From the Protein Data Bank

Michele Ceriotti, Piero Gasparotto, Benjamin Aaron Helfrecht, Federico Giberti

Rationalizing the structure and structure–property relations for complex materials such as polymers or biomolecules relies heavily on the identification of local atomic motifs, e.g., hydrogen bonds and secondary structure patterns, that are seen as buildin ...

2019

Mid-Infrared plasmonic nanoantennas for ultrasensitive detection of proteins and their secondary structure

Dordaneh Etezadi

Engineered plasmonic nanostructures have emerged as powerful sensing platforms and are promoting novel applications in various fields. By providing extreme field confinement down to molecular dimensions and enhancing light-matter interaction at the nanosca ...

EPFL2018

Fabrication and Characterization of Biodegradable, Thermal-Responsive Silk Composite Membrane

Jürgen Brugger, Xiao Sheng Zhang, Ya Wang

In this work, we present a study on a thermalresponsive biodegradable membrane composed of silk fibroin and iron oxide nanoparticles as potential candidate material for implantable smart drug delivery microsystems. Ethanol annealing increased the content o ...

2018

In situ Studies of Peptide and Protein Assemblies at the Solid-Liquid Interface

Bart Willem Stel

At the interface between science and engineering, there is the field of biomimicry: Innovations inspired by the observation of natural, evolutionary optimized biological structures and processes. To understand the challenges of biomimicry, the concept of â ...

EPFL2018

Fabrication and Characterization of Biodegradable, Thermal-Responsive Silk Composite Membrane

Jürgen Brugger, Xiao Sheng Zhang, Ya Wang

In this work, we present a study on a thermal-responsive biodegradable membrane composed of silk fibroin and iron oxide nanoparticles as potential candidate material for implantable smart drug delivery microsystems. Ethanol annealing increased the content ...

IEEE2018

Unusually Long-Lived Photocharges in Helical Organic Semiconductor Nanostructures

Jürgen Brugger, Andrzej Sienkiewicz, Holger Frauenrath, Valentin Flauraud, Jan Cornelius Brauer, Liangfei Tian, Thomas Schmaltz, Regina Judith Hafner

Photocharge generation and formation of long-lived charge carriers are relevant in photosynthesis, photocatalysis, photovoltaics, and organic electronics. A better understanding of the factors that determine these processes in synthetic polymer semiconduct ...

AMER CHEMICAL SOC2018

Nanoplasmonic mid-infrared biosensor for in vitro protein secondary structure detection

Giovanni Dietler, Hilal Lashuel, Hatice Altug, Francesco Simone Ruggeri, Dordaneh Etezadi, John Blaine Warner IV

Plasmonic nanoantennas offer new applications in mid-infrared (mid-IR) absorption spectroscopy with ultrasensitive detection of structural signatures of biomolecules, such as proteins, due to their strong resonant near-fields. The amide I fingerprint of a ...

Springer Nature2017

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