Concept

Self-replicating spacecraft

Publications associées (66)

Advancing Cell-Free Synthetic Biology: From sustained PURE protein synthesis to an isothermal one-pot DNA replication system

One of the goals of synthetic biology is the development of an artificial cell. Building an artificial cell from scratch will provide a deeper understanding of fundamental mechanisms and models in biology and promises to contribute towards building novel p ...

EPFL2024

uBFT: Microsecond-Scale BFT using Disaggregated Memory

Rachid Guerraoui, Antoine Murat, Mihail Igor Zablotchi, Athanasios Xygkis, Naama Ben David

We propose uBFT, the first State Machine Replication (SMR) system to achieve microsecond-scale latency in data centers, while using only 2f+1 replicas to tolerate f Byzantine failures. The Byzantine Fault Tolerance (BFT) provided by uBFT is essential as pu ...

2023

TFIIH moonlighting at telomeres

Joachim Lingner

Although telomeres are essential for chromosome stability, they represent fragile structures in our genome. Telomere shortening occurs during aging in cells lacking telomerase due to the end replication problem. In addition, recent work uncovered that the ...

COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT2022

The human telomeric proteome during telomere replication

Joachim Lingner, Thomas Frédéric Lunardi, Aleksandra Vancevska, Gérald Joseph Paul Lossaint, Chih-Yi Gabriela Lin

Telomere shortening can cause detrimental diseases and contribute to aging. It occurs due to the end replication problem in cells lacking telomerase. Furthermore, recent studies revealed that telomere shortening can be attributed to difficulties of the sem ...

OXFORD UNIV PRESS2021

Entre les eaux. Équipements de loisir et production d'énergie à Oberwald (VS)

Joséphine Bouvet

Au pied du Glacier du Rhône, à 1370 m d’altitude, Oberwald est le dernier village de la vallée de Conches, région réputée pour son ensoleillement, ses pistes de ski de fond et ses sentiers pédestres. À l’arrière du hameau, en lisière de forêt, une toiture ...

2020

Replicated state machines without replicated execution

Kirill Nikitin

This paper introduces a new approach to reduce end-to-end costs in large-scale replicated systems built under a Byzantine fault model. Specifically, our approach transforms a given replicated state machine (RSM) to another RSM where nodes incur lower costs ...

IEEE2020

Converse for Multi-Server Single-Message PIR with Side Information

Michael Christoph Gastpar, Su Li

Multi-server single-message private information retrieval is studied in the presence of side information. In this problem, K independent messages are replicatively stored at N non-colluding servers. The user wants to privately download one message from the ...

2020

System Support for Efficient Replication in Distributed Systems

Dragos-Adrian Seredinschi

Current online applications, such as search engines, social networks, or file sharing services, execute across a distributed network of machines. They provide non-stop services to their users despite failures in the underlying network. To achieve such a hi ...

EPFL2019

Dislocation multiplication by cross-slip and glissile reaction in a dislocation based continuum formulation of crystal plasticity

Modeling dislocation multiplication due to interaction and reactions on a mesoscopic scale is an important task for the physically meaningful description of stage II hardening in face centered cubic crystalline materials. In recent Discrete Dislocation Dyn ...

2019

Carbohydrate Self-Assembly at Surfaces: STM Imaging of Sucrose Conformation and Ordering on Cu(100)

Klaus Kern, Stephan Rauschenbach, Sabine Abb

Saccharides are ubiquitous biomolecules, but little is known about their interaction with, and assembly at, surfaces. By combining preparative mass spectrometry with scanning tunneling microscopy, we have been able to address the conformation and self-asse ...

2019

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