Concept
Maladie périodique
Publications associées (5)
Colchicine stimulates browning via antagonism of GABA receptor B and agonism of? 3-adrenergic receptor in 3T3-L1 white adipocytes
Colchicine has been used for therapeutic purposes and has attracted considerable attention because of its association with tubulin and the inhibition of small tubular polymerization. Although several studies have examined the possible preventive role of co ...
ELSEVIER IRELAND LTD2022Circadian clock- and feeding-dependent regulation of translation initiation and elongation in the liver
Circadian rhythms allow organisms to anticipate and adapt to periodic environmental changes related to the day-night cycle. These rhythms originate from a genetic network ticking in almost every cell of our body and the coordination between different organ ...
EPFL2018Impact of phosphorylation of alpha-synuclein in Parkinson's disease
Samareh Azeredo da Silveira Lajaunias
Parkinson's disease (PD) is characterized by the degeneration of dopamineric neurons of the substantia nigra pars compacta projecting to the striatum, and by the deposition of cytoplasmic protein inclusions. It is further defined by the persistent presence ...
EPFL2008Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome
Activation of caspase-1 and subsequent processing and secretion of the pro-inflammatory cytokine IL-1beta is triggered upon assembly of the inflammasome complex. It is generally believed that bacterial lipopolysaccharides (LPS) are activators of the inflam ...
Elsevier2004