Concept
Ribonucléotide
Publications associées (32)
Recycling of Polymerase Chain Reaction (PCR) Kits
Francesco Stellacci, Weina Liu, Yong Zhu
Polymerase chain reaction (PCR) kits have been used as common diagnosing tools during the outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, with daily worldwide usage in the millions. It is well known that at the beginn ...
AMER CHEMICAL SOC2023Investigation of physiological roles of AMPK-activated protein kinase y3
Clinical trials have shown that direct activators of an evolutionary-conserved metabolic sensor, AMP-activated protein kinase (AMPK), are beneficial in preventing/treating a range of metabolic disorders, including type 2 diabetes. These activators, includi ...
EPFL2021Shear Stress-Responsive Polymersome Nanoreactors Inspired by the Marine Bioluminescence of Dinoflagellates
Esther Amstad, Antoine Claude Jean Vian
Some marine plankton called dinoflagellates emit light in response to the movement of surrounding water, resulting in a phenomenon called milky seas or sea sparkle. The underlying concept, a shear-stress induced permeabilisation of biocatalytic reaction co ...
WILEY-V C H VERLAG GMBH2020The more the merrier: how homo-oligomerization alters the interactome and function of ribonucleotide reductase
Stereotyped as a nexus of dNTP synthesis, the dual-subunit enzyme - ribonucleotide reductase (RNR) - is coming into view as a paradigm of oligomerization and moonlighting behavior. In the present issue of `omics', we discuss what makes the larger subunit o ...
ELSEVIER SCI LTD2020Self-organization of parS centromeres by the ParB CTP hydrolase
Paolo De Los Rios, Stefano Zamuner
ParABS systems facilitate chromosome segregation and plasmid partitioning in bacteria and archaea. ParB protein binds centromeric parS DNA sequences and spreads to flanking DNA. We show that ParB is an enzyme that hydrolyzes cytidine triphosphate (CTP) to ...
2019Renal metabolism of hyperpolarized [1-13C]aspartate
Hikari Ananda Infinity Yoshihara
Aspartic acid is involved in several central metabolic pathways, including gluconeogenesis, the urea cycle, de novo nucleotide synthesis, the malate-aspartate shuttle, and via transmination the TCA cycle. The conversion in vivo of hyperpolarized [1-13C]pyr ...
2018Photophysics and Photochemistry of a DNA–Protein Cross-Linking Model: A Synergistic Approach Combining Experiments and Theory
Ursula Röthlisberger, Ivano Tavernelli, Sara Bonella, Mohammadhassan Valadan
The photophysical and photochemical properties of 5-benzyluracil and 5,6-benzyluracil, the latter produced by photocyclization of the former through irradiation with femtosecond UV laser pulses, are investigated both experimentally and theoretically. The a ...
2014Time-resolved photoelectron spectroscopy of adenine and adenosine in aqueous solution
Time-resolved photoelectron spectroscopy is applied to study the excited state dynamics of the DNA base adenine and its ribonucleoside adenosine in aqueous solution for pump and probe photon energies in the range between 4.66 eV and 5.21 eV. We follow the ...
Royal Soc Chemistry2013