Concept
Métalloprotéinase matricielle
Publications associées (99)
Unveiling breast cancer metastasis through an advanced X-ray imaging approach
Breast cancer is a significant global health burden, causing a substantial number of deaths. Systemic metastatic tumour cell dissemination is a major cause of poor outcomes. Understanding the mechanisms underlying metastasis is crucial for effective interv ...
Berlin2024TGF beta-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression
Cathrin Brisken, Andrea Agnoletto
Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive breast cancer. Virtually all women with DCIS are treated, despite evidence suggesting up to half would remain with stable, non-threatening, disease. Overtreatment thus presents a press ...
NATURE PORTFOLIO2023Hydrogels and conductive hydrogels for implantable bioelectronics
Stéphanie Lacour, Outman Akouissi, Emilio Fernández Lavado, Massimo Mariello, Kutay Sagdic
Hydrogels are a class of soft materials, which display unique biomimetic properties to biological tissues. Their mechanical properties, high water content, and porosity resemble that of extracellular matrix so that cell growth and proliferation can be reli ...
2023Macrophage depletion induces edema through release of matrix-degrading proteases and proteoglycan deposition
Colony-stimulating factor 1 receptor (CSF1R) blockade abates tumor-associated macrophage (TAM) infiltrates and provides marked clinical benefits in diffuse-type tenosynovial giant cell tumors. However, facial edema is a common adverse event associated with ...
AMER ASSOC ADVANCEMENT SCIENCE2021Recent Advances and Prospects in the Research of Nascent Adhesions
Aleksandra Radenovic, Ana-Suncana Smith
Nascent adhesions are submicron transient structures promoting the early adhesion of cells to the extracellular matrix. Nascent adhesions typically consist of several tens of integrins, and serve as platforms for the recruitment and activation of proteins ...
FRONTIERS MEDIA SA2020Integrin-Mediated Adhesion in the Unicellular Holozoan Capsaspora owczarzaki
In animals, cell-matrix adhesions are essential for cell migration, tissue organization, and differentiation, which have central roles in embryonic development [1-6]. Integrins are the major cell surface adhesion receptors mediating cell-matrix adhesion in ...
CELL PRESS2020