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We are interested in the mathematical modeling of the deformation of the human lung tissue, called the lung parenchyma, during the respiration process. The parenchyma is a foam-like elastic material containing millions of air-filled alveoli connected by a ...
World Scientific Publ Co Pte Ltd2015
Optical coherence tomography (OCT) is an interferometric imaging technique that can provide depth resolved cross-sectional views of biological tissue. OCT employs light with low temporal and yet high spatial coherence. The sample is illuminated point by po ...
Chronic obstructive pulmonary disease (COPD) is the 5(th) most prevalent disease worldwide leading to severe morbidity and mortality in developed countries. The disease is strongly associated with smoking, and can be characterized by progressive and irreve ...
ObjectiveTo construct a new pulmonary nodule diagnostic model with high diagnostic efficiency, non-invasive and simple to measure. MethodsThis study included 424 patients with radioactive pulmonary nodules who underwent preoperative 7-autoantibody (7-AAB) ...
In this paper we develop and study numerically a model to describe some aspects of sound propagation in the human lung, considered as a deformable and viscoelastic porous medium (the parenchyma) with millions of alveoli filled with air. Transmission of sou ...
EDP Sciences2014
Point-of-care ultrasound (POCUS) is an increasingly accessible skill, allowing for the decentralization of its use to nonspecialist healthcare workers to guide routine clinical decision-making. The advent of ultrasound-on-a-chip has transformed the technol ...
ELSEVIER SCI LTD2022
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Mechanical ventilation can damage the lungs, a condition called Ventilator-Induced Lung Injury (VILI). However, the mechanisms leading to VILI at the microscopic scale remain poorly understood. Here we investigated the within-tidal dynamics of cyclic recru ...
Main project. Chronic episodes of sudden pulmonary deterioration followed by insufficient recoveries from antibiotic treatments are the main driver of morbidity and mortality in Cystic Fibrosis (CF). Study of recovery is performed to improve CF care monito ...
Human alpha 1-antitrypsin (AAT) is an abundant acute phase glycoprotein expressing anti-protease and immunomodulatory activities, and is used as a biopharmaceutical to treat patients with inherited AAT deficiency. The pleiotropic properties of AAT provide ...
AREG-/- mice demonstrate impaired mammary development and form only rudimentary ductal epithelial trees, however, AREG-/- glands are still capable of undergoing alveologenesis and lactogenesis during pregnancy. Transplantation of AREG-/- mammary epithelial ...