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In visual backward masking, a target is followed by a blank screen (ISI - Inter-stimulus-interval) and, then, a mask which deteriorates target processing. Schizophrenic patients show strong but complex processing deficits in visual masking compared to heal ...
Contextual memory formation relies on the induction of new genes in the hippocampus. A polymorphism in the promoter of the transcription factor XBP1 was identified as a risk factor for Alzheimer's disease and bipolar disorders. XBP1 is a major regulator of ...
Recent genetic, behavioral, and clinical studies suggest that functional psychoses (schizophrenia, bipolar disorder, schizoaffective disorder), previously thought to be distinct from each other, may belong to one continuum. The shine-through masking paradi ...
Visual backward masking is a very sensitive tool for studying early visual processing deficits and a reliable endophenotype of schizophrenia. Mental diseases strongly overlap in many aspects, for example, in psychopathology, cognition, and genetics. Here, ...
Previous studies in rodents showed that chronic stress induces structural and functional alterations in several brain regions, including shrinkage of the hippocampus and the prefrontal cortex, which are accompanied by cognitive and emotional disturbances. ...
Objective: The cellular basis of variable symptoms in Huntington disease (HD) is unclear. One important possibility is that degeneration of the interneurons in the cerebral cortex, which play a critical role in modulating cortical output to the basal gangl ...
The crystal structure of a disordered form of Cr1/3NbS2 has been characterized using diffraction and inelastic scattering of synchrotron radiation. In contrast to the previously reported symmetry (P6322), the crystal can be ...
Balanced bipolar codes consist of sequences in which the symbols ‘−1’ and ‘+1’ appear equally often. Several generalizations to larger alphabets have been considered in literature. For example, for the q-ary alphabet {−q+1,−q+3, . . . , q−1}, known concept ...
The atmospheric CH4 increase from ∼0.7 to 1.68 p.p.m.v. over about the past 300 years which has been documented from analysis of air trapped in ice cores1-4 and from tropospheric measurements (see ref. 5 for example) is attributed to anthropogenic modifica ...
Obesity development during psychotropic treatments represents a major health issue in psychiatry. Melanin-concentrating hormone receptor 2 (MCHR2) is a central receptor involved in energy homeostasis. MCHR2 shares its promoter region with MCHR2-AS1, a long ...