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We review here the impact of early adversities on the development of violence and antisocial behaviour in humans, and present three etiological animal models of escalated rodent aggression, each disentangling the consequences of one particular adverse earl ...
Intrauterine Growth Restriction (IUGR) due to placental insufficiency affects 5-10% of all pregnancies and it is associated with a wide range of short and long-term neurodevelopmental disorders. Different approaches have been considered to understand IUGR ...
Magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) are widely used in the field of brain development and perinatal brain injury. Due to technical progress the magnetic field strength (B0) of MR systems has continuously increased, fa ...
Facial muscles drive whisker movements, which are important for active tactile sensory perception in mice and rats. These whisker muscles are innervated by cholinergic motor neurons located in the lateral facial nucleus. The whisker motor neurons receive s ...
Genetic approaches to control DNA expression in different brain areas have provided an excellent system to characterize gene function in health and disease of animal models. With respect to others, in utero electroporation of exogenous DNA into progenitor ...
Structural T1-weighted magnetic resonance imaging (MRI) provides sufficient anatomical details to measure and track changes in volumes of brain structures. The volumes of brain structures and changes in them can be used to study the effects of disease, tre ...
A deeper understanding of post-stroke plasticity is critical to devise more effective pharmacological and rehabilitative treatments. The GABAergic system is one of the key modulators of neuronal plasticity, and plays an important role in the control of "cr ...
Infancy is a critical period for brain development. Emerging evidence indicates that stress experienced during that period can have long-term programming effects on the brain and behavior. However, whether different time periods represent different vulnera ...
The human brain is a complex system able to continuously adapt. How and where brain activity is modulated by behavior can be studied with functional magnetic resonance imaging (fMRI), a non-invasive neuroimaging technique with excellent spatial resolution ...
DTI, may be the only feasible technique to study micorstructural changes occurring during the brain development. The main aims of this study was to design a complete new pipeline to perform micro-structural diffusion analysis in neonatal brain and to compa ...
