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Osamine
Publications associées (16)
Structure-function analysis of the cyclic β-1,2-glucan synthase from Agrobacterium tumefaciens
Henning Paul-Julius Stahlberg, Dongchun Ni
The synthesis of complex sugars is a key aspect of microbial biology. Cyclic beta-1,2-glucan (C beta G) is a circular polysaccharide critical for host interactions of many bacteria, including major pathogens of humans (Brucella) and plants (Agrobacterium). ...
Nature Portfolio2024Development of Sustainable Carbohydrate-Based Solvents by Acetal Functionalisation of Biomass
Organic solvents are ubiquitous in industrial and domestic applications from the production of pharmaceuticals to household consumer products. The negative impact of most traditional solvents, especially aprotic types, on the environment, health, and safet ...
EPFL2024Combining multi-stage ion mobility spectrometry with cryogenic infrared spectroscopy for glycan analysis
Structural analysis of biomolecules is essential to understanding biological processes. Among the various classes of biomolecules, glycans have gained significant attention recently due to their ubiquitous roles in biological systems. However, study of gly ...
EPFL2022Wastewater and green waste biorefinery Degradation of simple sugars using mixed cultures of purple non-sulfur bacteria: an insight into microbial interactions
Purple non-sulfur bacteria (PNSB) are phototrophic organisms that have raised interest for both industrial and domestic wastewater treatment and valorization because of their very high assimilation (~1 g CODX g-1 COD substrate) and valuable compounds produ ...
2019Cryogenic Vibrational Spectroscopy Provides Unique Fingerprints for Glycan Identification
Thomas Rizzo, Michael Zachary Kamrath, Chiara Masellis, Neelam Khanal
The structural characterization of glycans by mass spectrometry is particularly challenging. This is because of the high degree of isomerism in which glycans of the same mass can differ in their stereochemistry, attachment points, and degree of branching. ...
2017Establishing the Catalytic Mechanism of Human Pancreatic α-Amylase with QM/MM Methods
In this work, we studied the catalytic mechanism of human pancreatic α-amylase (HPA). Our goal was to determine the catalytic mechanism of HPA with atomic detail using computational methods. We demonstrated that the HPA catalytic mechanism consists of two ...
2015Modeling proton-induced damage on 2-deoxy-D-ribose. Conformational analysis
Modeling proton-induced damage in biological systems, in particular in DNA building blocks, is of major concern in studies on cancer proton therapy. This is indeed an extremely complex process and analysis of the mechanism at the molecular level is of cruc ...
Springer2014