Publications associées à Alpha motor neuron

Marinesco-Sjogren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS

Bernard Schneider, Céline Ruegsegger, Niran Maharjan

Mechanisms underlying motor neuron subtype selective endoplasmic reticulum (ER) stress and associated axonal pathology in amyotrophic lateral sclerosis (ALS) remain unclear. Here we show that the molecular environment of the ER between motor neuron subtype ...

Nature Publishing Group2015

Pathway-specific reorganization of projection neurons in somatosensory cortex during learning

Bernard Schneider, Atanas Stankov

In the mammalian brain, sensory cortices exhibit plasticity during task learning, but how this alters information transferred between connected cortical areas remains unknown. We found that divergent subpopulations of cortico-cortical neurons in mouse whis ...

Nature Publishing Group2015

Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration

Roman Chrast, Nathalie Marie Géraldine Bernard

Mutations in SIGMAR1, which encodes the Sigma 1 receptor, cause a familial form of amyotrophic lateral sclerosis, but the underlying molecular mechanisms are unclear. Bernard-Marissal et al. reveal that disruption of Sigma 1 receptor function disturbs endo ...

Oxford University Press2015

Modeling Brain Circuitry over a Wide Range of Scales

Pascal Fua, Graham Knott

If we are ever to unravel the mysteries of brain function at its most fundamental level, we will need a precise understanding of how its component neurons connect to each other. Electron Microscopes (EM) can now provide the nanometer resolution that is nee ...

Frontiers Research Foundation2015

Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates

Grégoire Courtine, Quentin Barraud, Pavel Musienko, Rubia van den Brand, Lucia Florinda Friedli Wittler

Experimental and clinical studies suggest that primate species exhibit greater recovery after lateralized compared to symmetrical spinal cord injuries. Although this observation has major implications for designing clinical trials and translational therapi ...

American Association for the Advancement of Science2015

Deficiency in monocarboxylate transporter 1 (MCT1) in mice delays regeneration of peripheral nerves following sciatic nerve crush

Pierre Magistretti, Sylvain Eric Lengacher, Luc Pellerin, Lin Jin

Peripheral nerve regeneration following injury occurs spontaneously, but many of the processes require metabolic energy. The mechanism of energy supply to axons has not previously been determined. In the central nervous system, monocarboxylate transporter ...

Elsevier2015

Quantitative Analysis of Myelin and Axonal Remodeling in the Uninjured Motor Network After Stroke

Jean-Philippe Thiran, Reto Meuli, Alessandro Daducci, Cristina Granziera, Djalel Eddine Meskaldji, Gunnar Krüger, Gloria Menegaz

Objectives: Contralesional brain connectivity plasticity was previously reported after stroke. This study aims at disentangling the biological mechanisms underlying connectivity plasticity in the uninjured motor network after an ischemic lesion. In particu ...

2015

Multiphoton microscopy in brain imaging

Graham Knott, Bohumil Maco, Ludovico Silvestri

Brain imaging is becoming an important field in the frame of the neurophotonics in correlations with other medical ones in neuroscience studying functional and morphological aspects. In this presentation an overview on multi photon imaging of the brain wil ...

Spie-Int Soc Optical Engineering2015

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Alpha motor neuron

Marinesco-Sjogren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS

Pathway-specific reorganization of projection neurons in somatosensory cortex during learning

Motor Control in the Mouse Whisker System

Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration

Modeling Brain Circuitry over a Wide Range of Scales

Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates

Deficiency in monocarboxylate transporter 1 (MCT1) in mice delays regeneration of peripheral nerves following sciatic nerve crush

Quantitative Analysis of Myelin and Axonal Remodeling in the Uninjured Motor Network After Stroke

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

Multiphoton microscopy in brain imaging

Graph Chatbot

Chattez avec Graph Search

Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration

Motor Control in the Mouse Whisker System

Marinesco-Sjogren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS

Modeling Brain Circuitry over a Wide Range of Scales

Pathway-specific reorganization of projection neurons in somatosensory cortex during learning

Deficiency in monocarboxylate transporter 1 (MCT1) in mice delays regeneration of peripheral nerves following sciatic nerve crush

Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates

Quantitative Analysis of Myelin and Axonal Remodeling in the Uninjured Motor Network After Stroke

Multiphoton microscopy in brain imaging

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq