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Publications associées (31)
Investigations about the Chemistry of Tetraarylethene- and Iridium-Based Luminophores
The work described in this thesis focuses on two classes of luminophores: tetraarylethene-based polymers and Ir(III) complexes with orthometalated ligands. Tetraarylethene-based polymers show aggregation-induced emission (AIE) and they are of interest for ...
EPFL2024The acid-mediated isomerization of iridium(iii) complexes with cyclometalated NHC ligands: kinetic vs. thermodynamic control
Kay Severin, Farzaneh Fadaei Tirani, Anastasia Gitlina
The isomerization of iridium(III) complexes with metalated N-heterocyclic carbene (NHC) ligands was studied. The fac isomers of complexes with 1-phenyl-3-methylbenzimidazolin-2-ylidene or 1-phenyl-3-benzylbenzimidazolin-2-ylidene ligands are transformed cl ...
2023Identification of N-glycan positional isomers by combining IMS and vibrational fingerprinting of structurally determinant CID fragments
Thomas Rizzo, Ahmed Ben Faleh, Stephan Warnke, Priyanka Bansal
While glycans are present on the surface of cells in all living organisms and play key roles in most biological processes, their isomeric complexity makes their structural characterization challenging. Of particular importance are positional isomers, for w ...
ROYAL SOC CHEMISTRY2022Visible light activated BINOL-derived chiroptical switches based on boron integrated hydrazone complexes
Chiral optical switches, which use light to control chirality in a reversible manner, offer unique properties and fascinating prospects in the areas of molecular switching and responsive systems, new photochromic materials and molecular data processing and ...
ROYAL SOC CHEMISTRY2022Combining multi-stage ion mobility spectrometry with cryogenic infrared spectroscopy for glycan analysis
Structural analysis of biomolecules is essential to understanding biological processes. Among the various classes of biomolecules, glycans have gained significant attention recently due to their ubiquitous roles in biological systems. However, study of gly ...
EPFL2022Enantioselective Total Synthesis of (+)-Nordasycarpidone, (+)-Dasycarpidone, and (+)-Uleine
Qian Wang, Jieping Zhu, Cédric Fung, Bastien Delayre
The structure of uleine type alkaloids is characterized by the presence of a bridged tetracyclic hexahydro-1H-1,5-methanoazocino[4,3-b]indole ring system 1. Various strategies have been developed to access this polycyclic structural motif. We report herein ...
2021A new approach for identifying positional isomers of glycans cleaved from monoclonal antibodies
Thomas Rizzo, Ahmed Ben Faleh, Stephan Warnke, Priyanka Bansal, Vasyl Yatsyna, Natalia Yalovenko
Glycosylation patterns in monoclonal antibodies (mAbs) can vary significantly between different host cell types, and these differences may affect mAbs safety, efficacy, and immunogenicity. Recent studies have demonstrated that glycan isomers with the termi ...
ROYAL SOC CHEMISTRY2021Characterising Structure and Stability of Materials using Machine Learning
The search of novel materials using in-silico high-throughput screening is emerging as a fundamental step in the pipeline of materials discovery, but its low yields in terms of synthesisable structures limit its effectiveness. In order to isolate configura ...
EPFL2020