Publications associées à Orthomyxoviridae

An Approximate Markov Model for the Wright-Fisher Diffusion and Its Application to Time Series Data

Jeffrey David Jensen, Anna Ferrer Admetlla

The joint and accurate inference of selection and demography from genetic data is considered a particularly challenging question in population genetics, since both process may lead to very similar patterns of genetic diversity. However, additional informat ...

Genetics Society America2016

Immobilization of the N-terminal helix stabilizes prefusion paramyxovirus fusion proteins

Matteo Dal Peraro, Luciano Andres Abriata, Albert Sanghoon Song

Parainfluenza virus 5 (PIV5) is an enveloped, single-stranded, negative-sense RNA virus of the Paramyxoviridae family. PIV5 fusion and entry are mediated by the coordinated action of the receptor-binding protein, hemagglutinin-neuraminidase (HN), and the f ...

Natl Acad Sciences2016

Positive Selection Drives Preferred Segment Combinations during Influenza Virus Reassortment

Jeffrey David Jensen, Matthieu Foll

Influenza A virus (IAV) has a segmented genome that allows for the exchange of genome segments between different strains. This reassortment accelerates evolution by breaking linkage, helping IAV cross species barriers to potentially create highly virulent ...

Oxford University Press2015

Periodic versus Intermittent Adaptive Cycles in Quasispecies Coevolution

Alexander Kevin Seeholzer

We study an abstract model for the coevolution between mutating viruses and the adaptive immune system. In sequence space, these two populations are localized around transiently dominant strains. Delocalization or error thresholds exhibit a novel interdepe ...

American Physical Society2014

Actively transporting virus like analytes with optofluidics for rapid and ultrasensitive biodetection

Hatice Altug, Arif Engin Cetin, Min Huang

Effective analyte delivery is essential to achieve rapid and sensitive biodetection systems. In this article, we present an actively controlled fluidic system integrated with a suspended plasmonic nanohole sensor to achieve superior analyte delivery effici ...

2013

Focal expression of adeno-associated viral-mutant tau induces widespread impairment in an APP mouse model

Patrick Aebischer, Bernard Schneider, Jean-Charles Bensadoun

Adeno-associated virus serotype 6 (AAV6) viral vectors encoding mutant and normal tau were used to produce focal tau pathology. Two mutant forms of tau were used; the P301S tau mutation is associated with neurofibrillary tangle formation in humans, and the ...

Elsevier Science Inc2013

Use of consensus sequences for the design of high density resequencing microarrays: the influenza virus paradigm

Stewart Cole, Iain Old

BACKGROUND: A resequencing microarray called PathogenID v2.0 has been developed and used to explore various strategies of sequence selection for its design. The part dedicated to influenza viruses was based on consensus sequences specific for one gene gene ...

BioMed Central2010

Early assessment of anxiety and behavioral response to novel swine-origin influenza A(H1N1)

Marcel Salathé

Since late April, 2009, a novel influenza virus A (H1N1), generally referred to as the "swine flu," has spread around the globe and infected hundreds of thousands of people. During the first few days after the initial outbreak in Mexico, extensive media co ...

Public Library of Science2009

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Orthomyxoviridae

An Approximate Markov Model for the Wright-Fisher Diffusion and Its Application to Time Series Data

Immobilization of the N-terminal helix stabilizes prefusion paramyxovirus fusion proteins

Positive Selection Drives Preferred Segment Combinations during Influenza Virus Reassortment

Periodic versus Intermittent Adaptive Cycles in Quasispecies Coevolution

Actively transporting virus like analytes with optofluidics for rapid and ultrasensitive biodetection

Focal expression of adeno-associated viral-mutant tau induces widespread impairment in an APP mouse model

Use of consensus sequences for the design of high density resequencing microarrays: the influenza virus paradigm

Early assessment of anxiety and behavioral response to novel swine-origin influenza A(H1N1)

Human immunodeficiency virus type 1 matrix protein interacts with cellular protein HO3

Replication properties of dUTPase-deficient mutants of caprine and ovine lentiviruses

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Chattez avec Graph Search

An Approximate Markov Model for the Wright-Fisher Diffusion and Its Application to Time Series Data

Focal expression of adeno-associated viral-mutant tau induces widespread impairment in an APP mouse model

Early assessment of anxiety and behavioral response to novel swine-origin influenza A(H1N1)

Human immunodeficiency virus type 1 matrix protein interacts with cellular protein HO3

Periodic versus Intermittent Adaptive Cycles in Quasispecies Coevolution

Use of consensus sequences for the design of high density resequencing microarrays: the influenza virus paradigm

Actively transporting virus like analytes with optofluidics for rapid and ultrasensitive biodetection

Replication properties of dUTPase-deficient mutants of caprine and ovine lentiviruses

Immobilization of the N-terminal helix stabilizes prefusion paramyxovirus fusion proteins

Positive Selection Drives Preferred Segment Combinations during Influenza Virus Reassortment