Publications associées à Diarrhée

Environmental determinants of access to shared sanitation in informal settlements: a cross-sectional study in Abidjan and Nairobi

Jérôme Chenal, Vitor Pessoa Colombo, Jürg Utzinger

Background Universal access to basic sanitation remains a global challenge, particularly in low- and middle-income countries. Efforts are underway to improve access to sanitation in informal settlements, often through shared facilities. However, access to ...

2023

Relating health benefits of water, sanitation, and hygiene services with the context of urban informal settlements: lessons from Côte d'Ivoire and Kenya

Vitor Pessoa Colombo

This thesis is inscribed in the recent efforts to reconnect urban planning and public health. It focused on the context of sub-Saharan African cities, for they offer invaluable lessons regarding environmental health determinants and potential solutions to ...

EPFL2023

Spatial Distributions of Diarrheal Cases in Relation to Housing Conditions in Informal Settlements: A Cross-Sectional Study in Abidjan, Côte d’Ivoire

Jérôme Chenal, Vitor Pessoa Colombo, Jürg Utzinger

In addition to individual practices and access to water, sanitation, and hygiene (WASH) facilities, housing conditions may also be associated with the risk of diarrhea. Our study embraced a broad approach to health determinants by looking at housing depriv ...

2023

Using Open-Access Data to Explore Relations between Urban Landscapes and Diarrhoeal Diseases in Côte d’Ivoire

Jérôme Chenal, Vitor Pessoa Colombo, Martí Bosch Padrós, Jürg Utzinger

Unlike water and sanitation infrastructures or socio-economic indicators, landscape features are seldomly considered as predictors of diarrhoea. In contexts of rapid urbanisation and changes in the physical environment, urban planners and public health man ...

2022

How Vibrio cholerae adapts to the environment: from cell shape transitions to antagonistic behavior

Leonardo Filipe Lemos Rocha

The bacterium Vibrio cholerae is the causative agent of the diarrheal disease cholera, which affects millions of people every year. Apart from being a human pathogen, V. cholerae is also a common member of aquatic habitats. Whilst the mechanism that allow ...

EPFL2022

Molecular insights into Vibrio cholerae’s intra-amoebal host-pathogen interactions

Graham Knott, Melanie Blokesch, Sandrine Stutzmann, Candice Stoudmann, Catherine Maclachlan, Natalia Carolina Drebes Dorr, Charles Ulric V Van der Henst, Tiziana Scrignari, Audrey Sophie Vanhove

Vibrio cholerae, which causes the diarrheal disease cholera, is a species of bacteria commonlyfound in aquatic habitats. Within such environments, the bacterium must defend itselfagainst predatory protozoan grazers. Amoebae are prominent grazers, withAcant ...

Nature Research2018

Oral application of Escherichia coli bacteriophage: safety tests in healthy and diarrheal children from Bangladesh

Patrick Descombes

A T4-like coliphage cocktail was given with different oral doses to healthy Bangladeshi children in a placebo-controlled randomized phase I safety trial. Fecal phage detection was oral dose dependent suggesting passive gut transit of coliphages through the ...

Wiley-Blackwell2017

Antibody-Mediated Trapping of Helminth Larvae Requires CD11b and Fc gamma Receptor I

Arne Seitz, Romain Guiet, Duncan-Bruce Sutherland, Nicola Harris, Benjamin John Marsland, Beatrice Volpe, Julia Esser-von Bieren, Manuel Kulagin

Infections with intestinal helminths severely impact on human and veterinary health, particularly through the damage that these large parasites inflict when migrating through host tissues. Host immunity often targets the motility of tissue-migrating helmin ...

American Association of Immunologists ; Oxford University Press2015

Glucose- but Not Rice-Based Oral Rehydration Therapy Enhances the Production of Virulence Determinants in the Human Pathogen Vibrio cholerae

Andrea Rinaldo, Melanie Blokesch, Enrico Bertuzzo, Flavio Finger, Juliane Kühn, Marino Gatto

Despite major attempts to prevent cholera transmission, millions of people worldwide still must address this devastating disease. Cholera research has so far mainly focused on the causative agent, the bacterium Vibrio cholerae, or on disease treatment, but ...

2014

Double-balloon jejunal perfusion to compare absorption of vitamin E and vitamin E acetate in healthy volunteers under maldigestion conditions

Martin Kussmann, Krisztina Nagy

BACKGROUND/OBJECTIVES: The vitamin E derivative, alpha-tocopheryl acetate, is often included in formulations used in enteral nutrition. In this respect, we compared alpha-tocopherol and alpha-tocopheryl acetate absorption under 'maldigestion' conditions, s ...

Nature Publishing Group2013