Concept

Pavlovian-instrumental transfer

Publications associées (28)

A striatal circuit balances learned fear in the presence and absence of sensory cues

Ralf Schneggenburger, Olexiy Kochubey, Michael Kintscher

During fear learning, defensive behaviors like freezing need to be finely balanced in the presence or absence of threat-predicting cues (conditioned stimulus, CS). Nevertheless, the circuits underlying such balancing are largely unknown. Here, we investiga ...

eLIFE SCIENCES PUBL LTD2023

Attractive and repulsive serial dependence: The role of task relevance, the passage of time, and the number of stimuli

David Pascucci, Gizay Ceylan

Visual decisions are attracted toward features of previous stimuli. This phenomenon, termed serial dependence, has been related to a mechanism that integrates present visual input with stimuli seen up to 10 to 15 s in the past. It is believed that this mec ...

2023

Striatal Dopamine Signals and Reward Learning

Carl Petersen, Sylvain Crochet, Yanqi Liu, Parviz Ghaderi, Mauro Pulin, Anthony Pierre Robert Renard, Christos Sourmpis, Pol Bech Vilaseca, Meriam Malekzadeh, Robin François Virginien Dard

We are constantly bombarded by sensory information and constantly making decisions on how to act. In order to optimally adapt behavior, we must judge which sequences of sensory inputs and actions lead to successful outcomes in specific circumstances. Neuro ...

Oxford2023

The effects of visual distractors on serial dependence

David Pascucci

Attractive serial dependence occurs when perceptual decisions are attracted toward previous stimuli. This effect is mediated by spatial attention and is most likely to occur when similar stimuli are attended at nearby locations. Attention, however, also in ...

Rockville2023

Dopamine Dynamics in Reward-based Learning

Jun Huang

Dopamine signals are thought to be important for reward-based learning and appear to play important roles in regulating synaptic plasticity in the nucleus accumbens and the striatum. However, the precise neuronal circuit mechanisms underlying the learning ...

EPFL2022

Acquisition-dependent modulation of hippocampal neural cell adhesion molecules by associative motor learning

Maria del Carmen Sandi Perez

It is widely accepted that some types of learning involve structural and functional changes of hippocampal synapses. Cell adhesion molecules neural cell adhesion molecule (NCAM), its polysialylated form polysialic acid to NCAM (PSA-NCAM), and L1 are promin ...

FRONTIERS MEDIA SA2022

Essays on the Role of Policy and Venture Financing in Clean Technology Innovation

Matthias David van den Heuvel

This thesis aims to provide novel analyses and data that improve the understanding of the financing of investments in clean technologies. In particular, this thesis explores the role that private and public actors play in supporting young innovative firms. ...

EPFL2022

Influence of amount of shear reinforcement and its post-yield response on the shear resistance of reinforced concrete members

Aurelio Muttoni, Miguel Fernández Ruiz, Frédéric Monney

The minimum amount of shear reinforcement to be provided in reinforced concrete members has been a topic of debate and research for decades without reaching a consensus. Defining such values is however instrumental to build in an economic manner and to saf ...

ERNST & SOHN2022

Uncovering the neural substrates of communication between the brain and ventral nerve cord in Drosophila melanogaster (italic)

Florian Aymanns

Despite a long history of research in motor control, the exact mechanism of how the brain communicates with the the invertebrate ventral nerve cord (VNC) and the vertebrate spinal cord on a single neuron basis remains largely elusive.Drosophila melanogaste ...

EPFL2022

Regulation of adenylyl cyclase 5 in striatal neurons confers the ability to detect coincident neuromodulatory signals

Ursula Röthlisberger, Siri Camee van Keulen, Daniele Narzi, Paolo Carloni

Author summary Adenylyl cyclases (ACs) are enzymes that can translate extracellular signals into the intracellular molecule cAMP, which is thus a 2nd messenger of extracellular events. The brain expresses nine membrane-bound AC variants, and AC5 is the dom ...

PUBLIC LIBRARY SCIENCE2019

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