Concept
Culture microbienne
Personnes associées (36)
Urs von Stockar
Originaire de Zurich, Urs von Stockar est né en1942. Ingénieur chimiste diplômé de l'EPFZ en 1967, il y est ensuite assistant au Laboratoire de chimie technique et, en 1973, soutient sa thèse couronnée par la médaille d'argent de l'EPFZ.
De 1973 à 1976, il travaille au département de génie chimique de l'Université de Californie. Il y enseigne et participe au développement d'un procédé technique pour la conversion biologique de la cellulose en alcool.
En 1977, il est ingénieur chimiste chez Ciba-Geigy. Fin 1977 il est nommé professeur extraordinaire à l'EPFL. Il dirige l'Institut de génie chimique en 1978/79 et en 1989/90. Il est professeur ordinaire en 1982. En 1982/83 et 1993/95, il dirige le Département de chimie. Son enseignement et sa recherche traitent des opérations de transfert de masse et de la biotechnologie, il s'intéresse également aux questions de bioénergétique et de biothermodynamique. Collaborant avec l'UNIL et l'ISREC, son équipe développe des procédés de fabrication d'anticorps monoclônaux spéciaux, capables de protéger les muqueuses humaines. En 1990 il est nommé professeur associé à l'Université de Genève. Il représente la Suisse dans un groupe d'experts de la Fédération européenne de biotechnologie. Après avoir siégé pendant plusieurs années dans son Comité de direction, il a été nommé président de la Fédération Européenne de Biotechnologie pour la période 1996-97. Depuis 1991, il dirige le Comité de coordination suisse pour la biotechnologie.
Diploma in Chemical Eng.-1967-ETHZ, CH
Ph.D.-1972-ETHZ, CH
Postdoc. Fellow-1973-76-Univ. of California, Berkeley, US
John McKinney
Professor John McKinney received his Ph.D. from The Rockefeller University (New York, NY) in 1994 for studies on cell cycle regulation in
Saccharomyces cerevisiae
in the laboratory of Fred Cross. From 1995 to 1998, he was a postdoctoral fellow in the laboratory of William Jacobs at the Albert Einstein College of Medicine (Bronx, NY), where he studied mechanisms of persistence in
Mycobacterium tuberculosis
. In 1999, he returned to Rockefeller University to establish his own laboratory as an Assistant (1999-2004) and then Associate (2004-2007) Professor. In July 2007, the lab relocated to the Global Health Institute in the School of Life Sciences at the École Polytechnique Fédérale de Lausanne (EPFL) in Switzerland, where McKinney is Professor and Head of the Laboratory of Microbiology and Microsystems (LMIC). Our research focuses on understanding the mechanistic basis of bacterial persistence in the context of host immunity and antimicrobial therapy, using
M. tuberculosis
as a "model" system.
Florian Maria Wurm
Florian Wurm received his academic training as a Biologist and Molecular Geneticist at the University of Giessen. He joined the Hoechst AG (Behringwerke) in Marburg as head of a laboratory in Virology. Working with immortalized mammalian cells for the establishment of production processes for alpha-interferons provided the first opportunity to combine basic research with medical application. In 1984 he joined Harvard Medical School in Boston as a Research Fellow in Molecular Biology. 1986 he took an offer from Genentech Inc. in San Francisco to work in Process Sciences on the development of large scale manufacturing processes for recombinant proteins. There he has held a number of leading positions and has acquired intimate knowledge in the generation of protein pharmaceuticals in mammalian cells in bioreactors (a number of which are now marketed products). In 1995 he joined the EPFL as a Professor for Biotechnology. Wurm has published more than 250 scientific papers and holds more than 20 patents/patent-applications. His H-index stands at 60 in 2021. He was Chairman (2005-2009) and is member of the Executive Board of the European Society of Animal Cell Technology (ESACT). He serves as a consultant to the pharmaceutical Biotech Industry, mainly in the fields of animal cell technology for recombinant protein production and in regulatory affairs. He works as a scientific reviewer and editior/asscciate editor for a number of international journals in the Biotech field. F.M. Wurm teaches classes to pre- and postgraduate students in the fields of Molecular and Cellular Biotechnology.
He was founder and Chief Scientific Officer of ExcellGene SA, a 2001 established company in Monthey, Switzerland. He took the position of President and CEO of ExcellGene in 2015. He retired from the CEO position in 2017 and continues to be President and Chief Scientific Officer of ExcellGene.
In 2008 Dr. Wurm was appointed Visiting Professor for Biotechnology at Jinan University in Guangzhou, China. He retired from his position at the EPFL in 2015. His laboratory is closed. With his team at ExcellGene and in collaboration with Dr. Paco Pino, Director of R&D, he continues to explore manufacturing sciences with animal cells in bioreactors.
Christof Holliger
Originaire d'Adliswil, Christof Holliger est né en 1959. Diplômé de l'ETHZ en biologie en 1984, il mène des travaux de recherche dans le domaine de la microbiologie environnementale à l'Université d'Agriculture de Wageningen (Pays-Bas) où il obtient son doctorat en Science de l'environnement en 1992. En 1992, il retourne en Suisse engagé comme collaborateur scientifique et chef de groupe à l'Institut Fédéral pour l'Aménagement, l'Epuration et la Protection des Eaux (EAWAG) à Kastanienbaum. Il y continue ses recherches sur la déchloruration réductrice, commencées aux Pays-Bas, et dirige des travaux sur la réduction des composés nitroaromatiques, la réduction du fer et la méthanogenèse psychrophile dans les sédiments des lacs. En octobre 1998, il est nommé professeur assistant en biotechnologie environnementale au Département de génie rural de l'EPFL. Ses recherches visent l'application des micro-organismes anaérobies pour le traitement des eaux résiduaires. En novembre 2004, il est nommé professeur associé et devient responsable du laboratoire de biotechnologie environnementale à la Faculté de l'Environnement naturel, architectural et construit. L'utilisation des techniques de la biologie moléculaire pour la caractérisation des communautés microbiennes impliquées dans le biotraitement de l'air, des eaux et des sols pollués est un outil clé dans les différents projets de recherche visants le développement des nouveaux procédés de traitement.
Pierre Magistretti
Pierre J. Magistretti is an internationally-recognized neuroscientist who has made significant contributions in the field of brain energy metabolism. His group has discovered some of the cellular and molecular mechanisms that underlie the coupling between neuronal activity and energy consumption by the brain.
This work has considerable ramifications for the understanding of the origin of the signals detected with the current functional brain imaging techniques used in neurological and psychiatric research (see for example Magistretti et al, Science, 283: 496 497, 1999). He is the author of over 100 articles published in peer-reviewed journals.
He has given over 80 invited lectures at international meetings or at universities in Europe and North America, including the 2000 Talairach Lecture at the Functional Mapping of the Human Brain Conference. In November 2000 he has been a Mc Donnel Visiting Scholar at Washington University School of Medicine.
Pierre J. Magistretti is the President-Elect (2002 2004) of the Federation of European Neuroscience Societies (FENS) which has a membership of over 15000 European neuroscientists. He has been first president of the Swiss Society for Neuroscience (1997-1999) and the first Chairman of the Department of Neurosciences of the University of Lausanne (1996 1998).
Pierre J. Magistretti is Professor of Physiology (since 1988) at the University of Lausanne Medical School. He has been Vice-Dean of the University of Lausanne Medical School from 1996 to 2000. Pierre Magistretti, is Director of the Brain Mind Institute at EPFL and Director of the Center for Psychiatric Neuroscience of the University of Lausanne and CHUV. He is also Director of the NCCR SYNAPSY "the synaptic bases of mental diseases".
POSITIONS AND HONORS
MAIN POSITION HELD
1988-2004 Professor of Physiology, University of Lausanne Medical School
1996-2000 Vice-Dean for Preclinical Departments, University of Lausanne Medical School
2001-2004 Chairman, Department of Physiology, University of Lausanne Medical School
2004-present Professor and Director, Center for Psychiatric Neuroscience, Department of Psychiatry, University of Lausanne Medical School and Hospitals (UNIL-CHUV) (Joint appointment with EPFL)
2005-2008 Professor and Co-Director, Brain Mind Institute, Federal Institute of Technology (EPFL), Lausanne (Joint appointment with UNIL-CHUV)
2007-present Chairman of the Scientific Advisory Board of Centre dImagerie Biomédicale (CIBM), an Imaging Consortium of the Universities, University Hospitals of Lausanne and Geneva and of Ecole Polytechnique Fédérale de Lausanne
2008-present Professor and Director, Brain Mind Institute, Federal Institute of Technology (EPFL), Lausanne Joint appointment with UNIL-CHUV)
2010-present Director, National Center for Competence in Research (NCCR)
The synaptic bases of mental diseases of the Swiss National Science Foundation
2010-present Secretary General, International Brain Research Organization (IBRO)
MAIN HONORS AND AWARDS
1997 Recipient of the Theodore-Ott Prize of the Swiss Academy of Medical Sciences
2001 Elected Member of Academia Europaea
2001 Elected Member of the Swiss Academy of Medical Sciences, ad personam
2002 Recipient of the Emil Kraepelin Guest Professorship, Max Planck Institute für Psychiatry, Münich
2006 Elected Professor at Collège de France, Paris, International Chair 2007-2008
2009 Goethe Award for Psychoanalytic Scholarship, Canadian Psychological Association
2011 Camillo Golgi Medal Award, Golgi Fondation
2011 Elected Member of the American College of NeuroPsychopharmacology (ACNP)
Sandro Carrara
Sandro Carrara a été nommé IEEE Fellow pour ses remarquables réalisations dans le domaine de la conception de biocapteurs CMOS à l'échelle nanométrique. Il a également reçu le prix "IEEE Sensors Council Technical Achievement Award" en 2016 pour son leadership dans le domaine émergent du co-design des interfaces Bio/Nano/CMOS. Il est un Professeur titulaire à l' EPFL à Lausanne (Suisse) et responsable du groupe de recherche "Bio/CMOS Interfaces" (BCI). Il est ancien professeur de biocapteurs optiques et électriques au Département de génie électrique et de biophysique (DIBE) de l'Université de Gênes (Italie) et ancien professeur de nanotechnologie à l'Université de Bologne (Italie). Il est titulaire d'un doctorat en biochimie et de biophysique de l'Université de Padoue (Italie), une master en physique de l'Université de Gênes (Italie), et un diplôme en électronique de l'Institut National de Technologie à Albenga (Italie). Ses intérêts scientifiques sont sur les phénomènes électriques de films nano-bio-structuré, et comprennent CMOS conception de biopuces à base de protéines et de l'ADN. Le long de sa carrière, il a publié 7 livres, l'un comme auteur avec Springer sur les interfaces Bio/CMOS et, plus récemment, un manuel de bioélectronique avec La prestigieuse Cambridge University Press. Il a également publié plus de 250 articles scientifiques et est l'auteur de 13 brevets. Il est maintenant chef rédacteur du Journal IEEE Sensors; il est également fondateur et chef rédacteur du Journal BioNanoScience par Springer, et rédacteur adjoint de IEEE Transactions on Circuits and Biomedical Systems. Il est membre du IEEE Sensors Council et de son comité exécutif. Il était membre du Conseil des gouverneurs de la IEEE Circuits And Systems Society (CASS). Il a été nommé IEEE conférencier émérite pour les années 2017-2019 pour le Conseil IEEE Sensors, et de la société CASS pour les années 2013-2014. Son travail a reçu plusieurs reconnaissances internationales: plusieurs Top-25 Hottest-articles (2004, 2005, 2008, 2009, et deux fois en 2012) publiés dans des journaux internationales très fort impact telles que Biosensors and Bioelectronics, Sensors And Actuators B, IEEE Sensors, et Thin Solid Films; un Award à une conference de l'OTAN en 1996 pour la contribution originale à la physique de la conductivité à électron unique dans les nano-particules; six "Best Paper Awards" pour des articles présentés à la conférence IEEE Sensors Conference en 2019 (Montreal), IEEE NGCAS en 2017 (Genoa), MOBIHEALTH en 2016 (Milan), IEEE PRIME en 2015 (Glasgow), en 2010 (Berlin) et en 2009 (Cork), un prix de la meilleure affiche au rencontre annuel de Nanotera en 2011 (Berne), et un prix de la meilleure affiche au NanoEurope Symposium en 2009 (Rapperswil). De 1997 à 2000, il a été membre d'un comité international au ELETTRA Synchrotron à Trieste. De 2000 à 2003, il était responsable scientifique d'un Programme national de recherche (PNR) dans le dépôt de nanobiotechnologie. Il était un expert internationalement estimé du comité d'évaluation de l'Académie de Finlande dans un programme de recherche pour les années 2010-2013. Il a été le président général (General Chair) de la Conférence IEEE BioCAS 2014, le premier conférence internationale dans le domaine des circuits et des systèmes pour les applications biomédicales.
Philippe Renaud
Philippe Renaud is Professor at the Microsystem Laboratory (LMIS4) at EPFL. He is also the scientific director of the EPFL Center of MicroNanoTechnology (CMI). His main research area is related to micronano technologies in biomedical applications (BioMEMS) with emphasis on cell-chips, nanofluidics and bioelectronics. Ph. Renaud is invloved in many scientifics papers in his research area. He received his diploma in physics from the University of Neuchâtel (1983) and his Ph.D. degree from the University of Lausanne (1988). He was postdoctoral fellow at University of California, Berkeley (1988-89) and then at the IBM Zürich Research Laboratory in Switzerland (1990-91). In 1992, he joined the Sensors and Actuators group of the Swiss Center for Electronics and Microtechnology (CSEM) at Neuchâtel, Switzerland. He was appointed assistant professor at EPFL in 1994 and full professor in 1997. In summer 1996, he was visiting professor at the Tohoku University, Japan. Ph. Renaud is active in several scientific committee (scientific journals, international conferences, scientific advisory boards of companies, PhD thesis committee). He is also co-founder of the Nanotech-Montreux conference. Ph. Renaud is committed to valorization of basic research through his involvement in several high-tech start-up companies.
Stewart Cole
Professor Stewart Cole is an international authority in bacterial molecular-genetics and genomics. He has made outstanding contributions in several fields including: bacterial anaerobic electron transport; genome analysis of retroviruses and papillomaviruses; antibiotic resistance mechanisms; and the molecular microbiology of toxigenic clostridia. His studies on isoniazid and multidrug resistance in Mycobacterium tuberculosis, together with his pioneering work on the pathogenicity, evolution and genomics of the tubercle and leprosy bacilli, have made him an undisputed leader in the field of mycobacterial research. The findings of his research are of direct relevance to public health and disease-control in both the developing world and the industrialised nations. He has published over 250 scientific papers and review articles, and holds many patents.
Johan Auwerx
Johan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.