Concept

Facteur neurotrophe

Publications associées (123)

Hormone Action in the Mammary Gland

A woman's breast cancer risk is affected by her reproductive history. The hormonal milieu also influences the course of the disease. The female reproductive hormones, estrogens, progesterone, and prolactin, have a major impact on breast cancer and control ...

2010

Purification & characterization of PceC protein involved in dehalorespiration by desulfitobacterium & dehalobacter

Christof Holliger, Julien Maillard, Aamani Rupakula Boyanapalli

Dehalorespiration is a process during which microbes derive energy by the reductive dehalogenation of chlorinated organic pollutants, by using them as electron acceptors. Characterization of the full dehalorespiration pathway in dehalogenating organisms is ...

2010

Innovation Management in the Postal Sector: What Are the Internal Factors Influencing Postal Operator’s Innovation Management?

Since the past decades, the postal sector is undergoing profound reform (liberalization). The major motivation for such reform processes was and still is the belief that liberalization and deregulation stimulates, among others, product and process innovati ...

2010

Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF

Patrick Aebischer, Romain Zufferey

This study assessed the potential for functional and anatomical recovery of the diseased aged primate nigrostriatal system, in response to trophic factor gene transfer. Aged rhesus monkeys received a single intracarotid infusion of MPTP, followed one week ...

2009

Effects of BDNF and other neuroprotectants on the neuropathology of Huntington's disease

Ozgün Gökce

Huntington's disease is an autosomal dominantly inherited neurodegenerative disorder characterized by progressive motor dysfunction, dementia, psychiatric symptoms, and weight loss, eventually leading to death. Postmortem analysis of the brains of HD patie ...

EPFL2009

Expression of brain-derived neurotrophic factor is not modulated by chronic mild stress in the rat hippocampus and amygdala

Pierre Magistretti, Jean-Luc Martin, Igor Allaman

Accumulating evidence supports a role for brain-derived neurotrophic factor (BDNF) in depression. However, most of these studies have been performed in animal models that have a low face validity with regard to the human disease. Here, we examined the regu ...

2009

Short-term striatal gene expression responses to brain-derived neurotrophic factor are dependent on MEK and ERK activation

Ozgün Gökce, Heike Runne

BACKGROUND: Brain-derived neurotrophic factor (BDNF) is believed to be an important regulator of striatal neuron survival, differentiation, and plasticity. Moreover, reduction of BDNF delivery to the striatum has been implicated in the pathophysiology of H ...

Public Library of Science2009

Glycogen metabolism as a marker of astrocyte differentiation

Pierre Magistretti, Igor Allaman, Luc Pellerin

Glycogen is a hallmark of mature astrocytes, but its emergence during astrocytic differentiation is unclear. Differentiation of E14 mouse neurospheres into astrocytes was induced with fetal bovine serum (FBS), Leukemia Inhibitory Factor (LIF), or Ciliary N ...

2009

In vitro and in vivo studies of new photoluminescent oxygen sensors for non-invasive intravascular pO 2 measurements

Hubert van den Bergh, Georges Wagnières, Patrycja Nowak-Sliwinska

The concentration of oxygen and its rate of consumption are important factors playing a role in PDT and radiotherapy. One of the methods for measuring the tissular oxygen partial pressure (pO 2) is based on the use of luminophores presenting an oxygen-depe ...

2009

Delta-like 1 participates in the specification of ventral midbrain progenitor derived dopaminergic neurons

Patrick Aebischer, Manuel Bauer

Delta-like 1 (Dlk1), a member of the Delta/Notch protein family, is expressed in the mouse ventral midbrain (VM) as early as embryonic day 11.5 (E11.5) followed by exclusive expression in tyrosine 3-monooxygenase (TH) positive neurons from E12.5 onwards. T ...

2008

Graph Chatbot

Chattez avec Graph Search

Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.

AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.

Connectez-vous pour utiliser Chat avec Graph Search