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To improve hydro-chemical modeling and forecasting, there is a need to better understand flood-induced variability in water chemistry and the processes controlling it in watersheds. In the literature, assumptions are often made, for instance, that stream c ...
Ferritin plays a central role in iron metabolism and is made of 24 subunits of 2 types: heavy chain and light chain. The ferritin heavy chain (FtH) has ferroxidase activity that is required for iron incorporation and limiting toxicity. The purpose of this ...
Dissolved organic nitrogen (DON) can act as a precursor of nitrogenous disinfection byproducts during oxidative water treatment. Quantification and characterization of DON are still challenging for waters with high concentrations of dissolved inorganic nit ...
Proteolytically stable peptide architectures are required for the development of long-acting peptide therapeutics. In this work, we found that a phage-selected bicyclic peptide antagonist exhibits an unusually high stability in vivo and subsequently deciph ...
The TGF-β homolog Decapentaplegic (Dpp) acts as a secreted morphogen in the Drosophila wing disc, and spreads through the target tissue in order to form a long range concentration gradient. Despite extensive studies, the mechanism by which the Dpp gradient ...
Myofibroblast-induced remodeling of collagenous extracellular matrix is a key component of our body's strategy to rapidly and efficiently repair damaged tissues; thus myofibroblast activity is considered crucial in assuring the mechanical integrity of vita ...
The goal of this project is to develop a new heuristic for pseudo-tree regeneration in S-DPOP. S-DPOP is a version of DPOP which should show performance improvements when resolving problems after small changes. Examples of such problems are: tracking movin ...
Intimal hyperplasia (IH) is a vascular remodeling process which often leads to failure of arterial bypass or hemodialysis access. Experimental and clinical work have provided insight in IH development; however, further studies under precise controlled cond ...
The objective of this study was to develop a model for the growth of Chinese Hamster Ovary (CHO) cells in shaken bioreactors. For this purpose a modified three parameters Gompertz equation was used to fit lag, exponential and stationary growth phases. Usin ...
The aim of this work is to set up mathematical models and numerical methods to investigate the mass transfer process occurring during the peritoneal dialysis (PD) therapy. More precisely the final goal is the set up of tools to find for each patient submit ...
