Publications associées à Syndrome du décalage horaire

Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior

Cédric Gobet, Sylviane Métairon, Frédéric Bruno Martin Gachon, Benjamin Dieter Weger

The synchronization of circadian clock depends on a central pacemaker located in the suprachiasmatic nuclei. However, the potential feedback of peripheral signals on the central clock remains poorly characterized. To explore whether peripheral organ circad ...

AMER ASSOC ADVANCEMENT SCIENCE2023

Uncovering personalized glucose responses and circadian rhythms from multiple wearable biosensors with Bayesian dynamical modeling

Felix Naef, Nicholas Edward Phillips

Wearable biosensors and smartphone applications can measure physiological variables over multiple days in free-living conditions. We measure food and drink ingestion, glucose dynamics, physical activity, heart rate (HR), and heart rate variability (HRV) in ...

CELL PRESS2023

Reduced order models for coupled systems

Niccolo' Discacciati

Efficient numerical simulations of coupled multi-component systems can be particularly challenging. This is mostly due to the complexity of their solutions, as mutual interactions may cause emergent behaviors, including synchronization and instabilities. V ...

EPFL2023

Optimized office lighting advances melatonin phase and peripheral heat loss prior bedtime

Jean-Louis Scartezzini, Mirjam Münch, Marta Benedetti, Lenka Maierova

Improving indoor lighting conditions at the workplace has the potential to support proper circadian entrainment of hormonal rhythms, sleep, and well-being. We tested the effects of optimized dynamic daylight and electric lighting on circadian phase of mela ...

Nature Research2022

Preliminary evidence that daily light exposure enhances the antibody response to influenza vaccination in patients with dementia

Jean-Louis Scartezzini

Enhancing lighting conditions in institutions for individuals with dementia improves their sleep, circadian rhythms and well-being. Here, we report first findings that exposure to brighter light during daytime may support the immune response to the annual ...

ELSEVIER2022

Exploring light exposure of hospital nurses working rapidly rotating shifts in relation to sleepiness and sleep

Steffen Lutz Hartmeyer

Nightshift work can negatively impact sleep, performance, and health. Careful manipulation of light exposure patterns can help reduce these negative effects but is challenging in conditions of rapidly rotating shiftwork and due to individual differences. A ...

IOP PUBLISHING LTD2021

Towards a wearable sensor for spectrally-resolved personal light monitoring

Marilyne Andersen, Forrest Simon Webler, Giorgia Chinazzo

Given the large impact that the spectrum and intensity of light can have on people's health and well-being, it is of fundamental importance to understand the properties of light received under normal living conditions. Historically, as research into the bi ...

2021

Kinetic modeling of lag times during photo-induced inactivation of E. coli in sunlit surface waters: Unraveling the pathways of exogenous action

César Pulgarin, Stefanos Giannakis, Jean Arnaud Troyon

This work presents a kinetic analysis of the exogenous photo-induced disinfection of E. coli in natural waters. Herein, the inactivation of bacteria by light and photo-generated transient species, i.e., hydroxyl radical (HO center dot), excited triplet sta ...

PERGAMON-ELSEVIER SCIENCE LTD2019

Chronotype: Implications for Epidemiologic Studies on Chrono-Nutrition and Cardiometabolic Health

Frédéric Bruno Martin Gachon

Chrono-nutrition is an emerging research field in nutritional epidemiology that encompasses 3 dimensions of eating behavior: timing, frequency, and regularity. To date, few studies have investigated how an individual's circadian typology, i.e., one's chron ...

OXFORD UNIV PRESS2019

How to assess alerting effects of daylight at the workplace? Learnings from semi-controlled studies

Marilyne Andersen, Victoria Eugenia Soto Magán

Daylight, in which we evolved, is naturally rich in the blue component of the spectrum and has key properties when it comes to impacts on body functioning. Current lifestyles are driving the emergence of a 24-hour society that spends most of the time indoo ...

2019