Concept
Fructose-6-phosphate
Publications associées (7)
Synthesis and characterization of an immobilizable photochemical molecular device for H-2-generation
With Ru-II(bpyMeP)(2)tpphzPtCl(2) (4) a molecular photocatalyst has been synthesized for visible-light-driven H-2-evolution. It contains the ligand bpyMeP (4,4'-bis(diethyl-(methylene)-phosphonate)-2,2'-bipyridine) with phosphate ester groups as prec ...
Royal Society of Chemistry2015Toward Quantitative Measurements of Enzyme Kinetics by Dissolution Dynamic Nuclear Polarization
Geoffrey Bodenhausen, Aurélien Bornet, Sami Jannin, Jonas Milani, Daniel Abergel
Dissolution dynamic nuclear polarization (D-DNP) experiments enabled us to study the kinetics of the enzymatic phosphorylation reaction of glucose to form glucose-6-phosphate (G6P) by hexokinase (HK), with or without the presence of an excess of G6P, which ...
2014Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme
Stewart Cole, Florence Pojer, Elizabeth Fullam
The transketolase (TKT) enzyme in Mycobacterium tuberculosis represents a novel drug target for tuberculosis treatment and has low homology with the orthologous human enzyme. Here, we report on the structural and kinetic characterization of the transketola ...
Royal Soc2012A Short and Convenient Synthesis of 1-Deoxymannojirimycin (DMJ) and N-oxy-Analogues from D-Fructose
Pierre Vogel, Sandrine Gerber, Claudia Bello
The ketonitrone 8 was prepared from D-fructose as an inexpensive starting material, and was used in a stereoselective synthesis of 1-deoxymannojirimycin (4), its previously unknown N-hydroxy analogue 15, as well as the polyhydroxylated ketonitrone 14. The ...
2009Heteronuclear two-dimensional NMR as a conformational probe of cellular phosphates
Heteronuclear 2-dimensional NMR was used to correlate the 1H and 31P chem. shifts of cellular phosphates. Exptl. spectra agree with theor. predictions based on a novel approach using subspectral anal. The spectra are sensitive to the homonuclear scalar cou ...
1979