Concept
Carence en thiamine
Publications associées (7)
Characterization of Cyclo His-Pro for the prevention and treatment of liver disease and muscular dystrophy
The natural compound Cyclo Histidine-Proline (CHP) was initially discovered in the brain, but thereafter evaluated in the context of diabetes because of its hypoglycemic action. The pharmacokinetics and the toxicological profile of CHP showed it can be dos ...
EPFL2023Transient vitamin B5 starving improves mammalian cell homeostasis and protein production
Maintaining a metabolic steady state is essential for an organism's fitness and survival when confronted with environmental stress, and metabolic imbalance can be reversed by exposing the organism to fasting. Here, we attempted to apply this physiological ...
ACADEMIC PRESS INC ELSEVIER SCIENCE2020ErbB receptor signaling directly controls oligodendrocyte progenitor cell transformation and spontaneous remyelination after spinal cord injury
We recently discovered a novel role for neuregulin-1 (Nrg1) signaling in mediating spontaneous regenerative processes and functional repair after spinal cord injury (SCI). We revealed that Nrg1 is the molecular signal responsible for spontaneous functional ...
2019Gait Control and Locomotor Recovery after Spinal Cord Injury
The gait of patients with an incomplete spinal cord injury (iSCI) has been studied previously. The most widely examined parameters to characterize iSCI gait are walking speed and time-distance measures (e.g., step length, step frequency, gait-cycle phases) ...
ETH Zurich2014Hes1 as a Mediator of Notch Signalling in T-cell Development and Notch1- Induced T-ALL
The evolutionarily conserved Notch signalling pathway controls a broad spectrum of cell fate decisions in organisms as diverse as fruit flies and mice. Whithin the murine haematopoietic system, Notch1 is indispensable for T cell development as conditional ...
EPFL2010Quantitative characterization of a recombinant Pichia pastoris Mut+ strain secreting avidin using transient continuous cultures
The objective of this thesis was to characterize the growth stoichiometry, the specific recombinant protein productivity and the regulation of the alcohol oxidase (AOX) enzyme of a Pichia pastoris Mut+ strain, performing conventional chemostat cultures and ...
EPFL2007