Concept

Médicament psychotrope

Publications associées (77)

Nanomechanics of multidomain neuronal cell adhesion protein contactin revealed by single molecule AFM and SMD

Giovanni Dietler, Andrzej Kulik, Karolina Anna Mikulska Ruminska

Contactin-4 (CNTN4) is a complex cell adhesion molecule (CAM) localized at neuronal membranes, playing a key role in maintaining the mechanical integrity and signaling properties of the synapse. CNTN4 consists of six immunoglobulin C2 type (IgC2) domains a ...

Springer Nature2017

Physics-based Reconstruction and Animation of Humans

Alexandru Eugen Ichim

Creating digital representations of humans is of utmost importance for applications ranging from entertainment (video games, movies) to human-computer interaction and even psychiatrical treatments. What makes building credible digital doubles difficult is ...

EPFL2017

Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines

Friedhelm Christoph Hummel

Low intensity transcranial electrical stimulation (TES) in humans, encompassing transcranial direct current (tDCS), transcutaneous spinal Direct Current Stimulation (tsDCS), transcranial alternating current (tACS), and transcranial random noise (tRNS) stim ...

2017

Multisensory and sensorimotor origins of the sense of self

Polona Pozeg

Cognitive neuroscience has increasingly focused on studying the subject, i.e. the self, of conscious experience. In order to be the subject of an experience, we generally experience owning a physical body, being located within that body, and being able to ...

EPFL2016

Impact of HSD11B1 polymorphisms on BMI and components of the metabolic syndrome in patients receiving psychotropic treatments

Pierre Magistretti, Murielle Bochud, Aurélie Delacrétaz

Background Metabolic syndrome (MetS) associated with psychiatric disorders and psychotropic treatments represents a major health issue. 11 beta-Hydroxysteroid dehydrogenase type 1 (11 beta-HSD1) is an enzyme that catalyzes tissue regeneration of active cor ...

Lippincott Williams & Wilkins2015

Association of PCK1 with Body Mass Index and Other Metabolic Features in Patients With Psychotropic Treatments

Pierre Magistretti, Aurélie Delacrétaz

Weight gain is a major health problem among psychiatric populations. It implicates several receptors and hormones involved in energy balance and metabolism. Phosphoenolpyruvate carboxykinase 1 is a rate-controlling enzyme involved in gluconeogenesis, glyce ...

Lippincott, Williams & Wilkins2015

Automatic target validation based on neuroscientific literature mining for tractography

Jean-Cédric Chappelier, Sean Lewis Hill, Jocelyne Bloch, Bogdan Draganski, Renaud Luc Richardet, Xavier Vasques, David Slater

Target identification for tractography studies requires solid anatomical knowledge validated by an extensive literature review across species for each seed structure to be studied. Manual literature review to identify targets for a given seed region is ted ...

Frontiers Research Foundation2015

Hippocampal neuroligin-2 links early-life stress with impaired social recognition and increased aggression in adult mice

Maria del Carmen Sandi Perez, Jocelin Grosse, Alexandre Claude Gustave Bacq, Céline Fournier

Early-life stress is a key risk factor for the development of neuropsychiatric disorders later in life. Neuronal cell adhesion molecules have been strongly implicated in the pathophysiology of psychiatric disorders and in modulating social behaviors associ ...

2015

Tetrahydrobiopterin Biosynthesis as a Potential Target of the Kynurenine Pathway Metabolite Xanthurenic Acid

Kai Johnsson, Rudolf Hovius, Hirohito Haruki, Miriam Grønlund Pedersen

Tryptophan metabolites in the kynurenine pathway are up-regulated by pro-inflammatory cytokines or glucocorticoids, and are linked to anti-inflammatory and immunosuppressive activities. In addition, they are up-regulated in pathologies such as cancer, auto ...

Amer Soc Biochemistry Molecular Biology Inc2015

Influence of MCHR2 and MCHR2-AS1 Genetic Polymorphisms on Body Mass Index in Psychiatric Patients and In Population-Based Subjects with Present or Past Atypical Depression

Pierre Magistretti, Aurélie Delacrétaz

Obesity development during psychotropic treatments represents a major health issue in psychiatry. Melanin-concentrating hormone receptor 2 (MCHR2) is a central receptor involved in energy homeostasis. MCHR2 shares its promoter region with MCHR2-AS1, a long ...

Public Library of Science2015

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