Concept

Système biologique

Publications associées (113)

Real-Time Audio-Visual Analysis for Multiperson Videoconferencing

Hervé Bourlard, Jean-Marc Odobez, Petr Motlicek, Danil Korchagin

We describe the design of a system consisting of several state-of-the-art real-time audio and video processing components enabling multimodal stream manipulation (e.g., automatic online editing for multiparty videoconferencing applications) in open, uncons ...

2013

From ‘Omics to Otoliths: Responses of an Estuarine Fish to Endocrine Disrupting Compounds across Biological Scales

Endocrine disrupting chemicals (EDCs) cause physiological abnormalities and population decline in fishes. However, few studies have linked environmental EDC exposures with responses at multiple tiers of the biological hierarchy, including population-level ...

Public Library of Science2013

Benchmarking Image-Processing Algorithms for Biomicroscopy: Reference Datasets and Perspectives

Michaël Unser, Daniel Sage, Cédric René Jean Vonesch, Hagay Kirshner, Stamatios Lefkimmiatis

As the field of bioimage informatics matures, the issue of the validation of image reconstruction algorithms and the definition of proper performance criteria becomes more pressing. In this work, we discuss benchmarking aspects of fluorescence microscopy q ...

EUSIPCO2013

Identification of Feasible Metabolic Fluxes and Metabolite Concentrations using Large-scale Kinetic Models

Vassily Hatzimanikatis, Ljubisa Miskovic, Keng Cher Soh, Anirikh Chakrabarti

The constraints imposed during modeling must satisfy biologically representative phenotypes of the studied organism. Simultaneously, identification and analysis of these constraints enhances our understanding of the evolution/operational paradigms of the o ...

2013

Proteolytic Processing Regulates Placental Growth Factor Activities

Jeffrey Alan Hubbell, Stéphanie Elisabeth Metzger, Martin Ehrbar, Manuel Koch

Placental growth factor (PlGF) is a critical mediator of blood vessel formation, yet mechanisms of its action and regulation are incompletely understood. Here we demonstrate that proteolytic processing regulates the biological activity of PlGF. Specificall ...

Amer Soc Biochemistry Molecular Biology Inc2013

X-ray mosaic nanotomography of large microorganisms

Marco Stampanoni

Full-field X-ray microscopy is a valuable tool for 3D observation of biological systems. In the soft X-ray domain organelles can be visualized in individual cells while hard X-ray microscopes excel in imaging of larger complex biological tissue. The field ...

2012

Large-Scale Production of Microcrystals and Precipitates of Proteins and Their Complexes

Geoffrey Bodenhausen, Daniel Abergel

The optimum conditions for the formation of plate-like and urchin-like microcrystals of biomolecules and their transfer to rotors for solid-state NMR spectroscopy depend on a variety of factors, of which minimizing the manipulation of the microcrystals and ...

Amer Chemical Soc2012

Impact analysis of a flexible air transportation system

Michel Bierlaire, Claudio Leonardi, Matteo Salani, Bilge Atasoy

An innovative modular aircraft, called Clip-Air, is being designed at Ecole Polytechnique Federale de Lausanne (EPFL). The novelty of Clip-Air from a transportation system viewpoint is its flexibility due to the decoupling of load and carrying units. In th ...

2012

Adaptive Models for Gene Networks

Ali H. Sayed

Biological systems are often treated as time-invariant by computational models that use fixed parameter values. In this study, we demonstrate that the behavior of the p53-MDM2 gene network in individual cells can be tracked using adaptive filtering algorit ...

Public Library of Science2012

Noise and oscillations in biological systems: Multidisciplinary approach between experimental biology, theoretical modelling and synthetic biology

Andrew Charles Oates

Rapid progress of experimental biology has provided a huge flow of quantitative data, which can be analyzed and understood only through the application of advanced techniques recently developed in theoretical sciences. On the other hand, synthetic biology ...

2012

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