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Retroelements are important evolutionary forces but can be deleterious if left uncontrolled. Members of the human APOBEC3 family of cytidine deaminases can inhibit a wide range of endogenous, as well as exogenous, retroelements. These enzymes are structura ...
In this paper, we discuss an important problem of the selection of the neighborhood radius in the learning schemes of the Winner Takes Most Kohonen neural network. The optimization of this parameter is essential in case of hardware realization of the netwo ...
Uncertain environments pose a tremendous challenge to populations: The selective pressures imposed by the environment can change so rapidly that adaptation by mutation alone would be too slow. One solution to this problem is given by the phenomenon of stoc ...
The Astar algorithm, which forms the backbone of vehicle navigation systems, is capable of producing only one path. Given uncertainty about link travel times, there is interest in algorithms that can deliver all the paths that may be optimal, termed collec ...
The problem of feature selection has been thoroughly analyzed in the context of pattern classification, with the purpose of avoiding the curse of dimensionality. However, in the context of multimodal signal processing, this problem has been studied less. O ...
Many collection development practices are relevant for electronic books as well as for their paper counterparts: selection, acquisition, management, cataloguing, evaluation, etc. Over the years, libraries have developed best practices and tools to tackle t ...
Antagonistic coevolution between hosts and parasites is known to affect selection on recombination in hosts. The Red Queen Hypothesis (RQH) posits that genetic shuffling is beneficial for hosts because it quickly creates resistant genotypes. Indeed, a larg ...
Extinction, recolonization and local adaption are common in natural spatially structured populations. Understanding their effect upon genetic variation is important for systems such as GMO management, or avoidance of drug resistance. Theoretical studies on ...
The purpose of this review is to describe the current status and to highlight several emerging trends in the manufacture of recombinant therapeutic proteins in cultivated mammalian cells. focusing on Chinese hamster ovary cells as the major production host ...
We develop an efficient learning framework to construct signal dictionaries for sparse representation by selecting the dictionary columns from multiple candidate bases. By sparse, we mean that only a few dictionary elements, compared to the ambient signal ...
