Concept
Bacterial secretion system
Publications associées (68)
Capsular Polysaccharide Restrains Type VI Secretion in Acinetobacter baumannii
Melanie Blokesch, Loriane Bader, Mary-Claude Croisier-Coeytaux, Nicolas Olmo Flaugnatti
The type VI secretion system (T6SS) is a sophisticated, contact-dependent nanomachine involved in interbacterial competition. To function effectively, the T6SS must penetrate the membranes of both attacker and target bacteria. Structures associated with th ...
2024The tip protein PAAR is required for the function of the type VI secretion system
Bacteria are constantly competing to colonize crowded ecological niches, such as the human gut. The type VI secretion system (T6SS) is a critical bacterial weapon in this warfare. It resembles a crossbow with a poisoned arrow allowing bacteria to inject to ...
Washington2023Recent advances in therapeutic targets identification and development of treatment strategies towards Pseudomonas aeruginosa infections
The opportunistic human pathogen Pseudomonas aeruginosa is the causal agent of a wide variety of infections. This non-fermentative Gram-negative bacillus can colonize zones where the skin barrier is weakened, such as wounds or burns. It also causes infecti ...
BMC2023Structural Basis of Ligand Selectivity by a Bacterial Adhesin Lectin Involved in Multispecies Biofilm Formation
Carbohydrate recognition by lectins governs critical host-microbe interactions. MpPA14 (Marinomonas primoryensis PA14 domain) lectin is a domain of a 1.5-MDa adhesin responsible for a symbiotic bacterium-diatom interaction in Antarctica. Here, we show that ...
Washington2021