Concept

Maladie coronarienne

Publications associées (112)

Designing Safer Analgesics via mu-Opioid Receptor Pathways

Pain is both a major clinical and economic problem, affecting more people than diabetes, heart disease, and cancer combined. While a variety of prescribed or over-the-counter (OTC) medications are available for pain management, opioid medications, especial ...

Elsevier Science London2017

Role of ERK1/2 activation and nNOS uncoupling on endothelial dysfunction induced by lysophosphatidylcholine

Nikolaos Stergiopoulos, Luciano Dos Santos Aggum Capettini

Background and aims: Lysophosphatidylcholine (LPC) - a main component of oxidized LDL -is involved in endothelial dysfunction that precedes atherosclerosis, with an increased superoxide anions and a reduced NO production via endothelial NO synthase (eNOS) ...

Elsevier2017

An asymptotic formula for boundary potential perturbations in a semilinear elliptic equation related to cardiac electrophysiology

Andrea Manzoni

In this paper, we provide a representation formula for boundary voltage perturbations caused by internal conductivity inhomogeneities of low volume fraction in a simplified monodomain model describing the electrical activity of the heart. We derive such a ...

World Scientific Publishing2016

The formulation of hyperpolarized 13C pyruvate solutions influences the labeling of myocardial metabolites in vivo

Arnaud Comment, Josefina Adriana Maria Bastiaansen, Hikari Ananda Infinity Yoshihara

In developing an intact rat model for myocardial ischemia using hyperpolarized 13C pyruvate, different compound formulations were evaluated. Infusion of 4-hydroxy-TEMPO-polarized sodium [1-13C]pyruvate was compared to an equivalent dose of buffered trityl ...

2016

MATHICSE Technical Report : A fast virtual surgery platform for many scenarios haemo-dynamics of patient-specific coronary artery bypass grafts

Alfio Quarteroni, Gianluigi Rozza, Andrea Manzoni, Elena Faggiano

A fast computational framework is devised to the study of several configurations of patient-specific coronary artery by-pass grafts. This is especially useful to perform a sensitivity analysis of the haemodynamics for different flow conditions occurring in ...

MATHICSE2016

Fast simulations of patient-specific haemodynamics of coronary artery bypass grafts based on a POD-Galerkin method and a vascular shape parametrization

Alfio Quarteroni, Gianluigi Rozza, Andrea Manzoni, Elena Faggiano

In this work a reduced-order computational framework for the study of haemodynamics in three-dimensional patient-specific configurations of coronary artery bypass grafts dealing with a wide range of scenarios is proposed. We combine several efficient algor ...

Elsevier2016

Intra-Arterial Drug and Light Delivery for Photodynamic Therapy Using Visudyne (R): Implication for Atherosclerotic Plaque Treatment

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Manish Jain

Photodynamic therapy (PDT), which is based on the activation of photosensitizers with light, can be used to reduce plaque burden. We hypothesized that intra-arterial photosensitizer administration and photo-activation will lead to high and rapid accumulati ...

2016

Ultrafast laser ablation for targeted atherosclerotic plaque removal

Demetri Psaltis, Donald Benjaman Conkey, Thomas Jean Victor Marie Lanvin, Laurent Descloux

Coronary artery disease, the main cause of heart disease, develops as immune cells and lipids accumulate into plaques within the coronary arterial wall. As a plaque grows, the tissue layer (fibrous cap) separating it from the blood flow becomes thinner and ...

Spie-Int Soc Optical Engineering2015

MATHICSE Technical Report : Fast simulations of patient-specific haemodynamics of coronary artery bypass grafts based on a Pod-Galerkin method and a vascular shape parametrization

Alfio Quarteroni, Gianluigi Rozza, Andrea Manzoni, Elena Faggiano

MATHICSE2015

An Intact Small Animal Model of Myocardial Ischemia-Reperfusion: Characterization of Metabolic Changes by Hyperpolarized 13C MR Spectroscopy

Arnaud Comment, Josefina Adriana Maria Bastiaansen, Hikari Ananda Infinity Yoshihara

Hyperpolarized carbon-13 magnetic resonance spectroscopy ((13)C MRS) enables the sensitive and noninvasive assessment of the metabolic changes occurring during myocardial ischemia-reperfusion. Ischemia-reperfusion models using hyperpolarized (13)C MRS are ...

2015

Graph Chatbot

Chattez avec Graph Search

Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.

AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.

Connectez-vous pour utiliser Chat avec Graph Search