Concept
Cancer de l'anus
Publications associées (70)
Multiomic analysis of HER2-enriched and AR-positive breast carcinoma with apocrine differentiation and an oligometastatic course: a case report
Breast carcinoma is the most prevalent cancer among women globally. It has variable clinical courses depending on the stage and clinical-biological features. This case report describes a 56-year-old female with invasive breast cancer without estrogen or pr ...
FRONTIERS MEDIA SA2023Metabolic dependencies of metastasis-initiating cells in female breast cancer
Albert Santamaria Martinez, Pierre Vincent Dessen, Angela Madurga Alonso, Candice Megan T Young, Laurent Nam Ky Beziaud
Understanding the mechanisms that enable cancer cells to metastasize is essential in preventing cancer progression. Here we examine the metabolic adaptations of metastasis-initiating cells (MICs) in female breast cancer and how those shape their metastatic ...
Berlin2023Pan-cancer atlas of somatic core and linker histone mutations
Recent genomic data points to a growing role for somatic mutations altering core histone and linker histone-encoding genes in cancer. However, the prevalence and the clinical and biological implications of histone gene mutations in malignant tumors remain ...
2023Protein Engineering for Personalized therapy and diagnosis
Protein Engineering, especially protein post-translational modification (PTM), ex-tends proteomes in a more complex way than one can expect from analysis of their encod-ing genomes. It can activate or deactivate certain catalytic functions, add new desired ...
EPFL2022Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion
Douglas Hanahan, Nadine Fournier, Krisztian Homicsko, Mélanie Louise Tichet, Agnieszka Alicja Chryplewicz, Jeremy Gilles Louis Guillot, Simge Yücel, Mohammad Sadegh Saghafinia, Inti Zlobec, Yuqing Xie, Dalya Ataca, Qiqun Zeng, Fleuriane Marie Tryskele Laurene Gallean, Peng Zhang, Lucine Christe
Many human cancers manifest the capability to circumvent attack by the adaptive immune system. In this work, we identified a component of immune evasion that involves frequent up-regulation of fragile X mental retardation protein (FMRP) in solid tumors. FM ...
Washington2022