Publications associées à Noyau suprachiasmatique

The genomic landscape of human cellular circadian variation points to a novel role for the signalosome

Frédéric Bruno Martin Gachon, Konstantin Popadin, Daniel Alain Dominique Marie Mauvoisin

The importance of natural gene expression variation for human behavior is undisputed, but its impact on circadian physiology remains mostly unexplored. Using umbilical cord fibroblasts, we have determined by genome-wide association how common genetic varia ...

Elife Sciences Publications Ltd2017

Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver

Felix Naef, Loïc Dayon, Frédéric Bruno Martin Gachon, Martin Kussmann, Daniel Alain Dominique Marie Mauvoisin, Jingkui Wang, Florian Atger, Federico Sizzano

Diurnal oscillations of gene expression controlled by the circadian clock and its connected feeding rhythm enable organisms to coordinate their physiologies with daily environmental cycles. While available techniques yielded crucial insights into regulatio ...

Elsevier2017

Transcriptional regulatory logic of the diurnal cycle in the mouse liver

Matteo Dal Peraro, Bart Deplancke, Felix Naef, Frédéric Bruno Martin Gachon, Benjamin Dieter Weger, Sunil Kumar Raghav, Nouria Hernandez, Irina Krier, Guillaume Rey, Alexandra Styliani Kalantzi, Jonathan Aryeh Sobel

Many organisms exhibit temporal rhythms in gene expression that propel diurnal cycles in physiology. In the liver of mammals, these rhythms are controlled by transcription-translation feedback loops of the core circadian clock and by feeding-fasting cycles ...

Public Library of Science2017

PDF Signaling Is an Integral Part of the Drosophila Circadian Molecular Oscillator

Bart Deplancke, Jean-Daniel Feuz

Circadian clocks generate 24-hr rhythms in physiology and behavior. Despite numerous studies, it is still uncertain how circadian rhythms emerge from their molecular and neural constituents. Here, we demonstrate a tight connection between the molecular and ...

Elsevier2016

Extensive Regulation of Diurnal Transcription and Metabolism by Glucocorticoids

Cédric Gobet, Frédéric Bruno Martin Gachon, Benjamin Dieter Weger, Meltem Weger

Altered daily patterns of hormone action are suspected to contribute to metabolic disease. It is poorly understood how the adrenal glucocorticoid hormones contribute to the coordination of daily global patterns of transcription and metabolism. Here, we exa ...

Public Library Science2016

Temperature regulates splicing efficiency of the cold-inducible RNA-binding protein gene Cirbp

Felix Naef, Saeed Omidi Klishami

In mammals, body temperature fluctuates diurnally around a mean value of 36 degrees C-37 degrees C. Despite the small differences between minimal and maximal values, body temperature rhythms can drive robust cycles in gene expression in cultured cells and, ...

Cold Spring Harbor Laboratory2016

Sustained Sleep Fragmentation Induces Sleep Homeostasis in Mice

Pierre Magistretti, Jean-Marie Petit, Maxime Olivier Baud

Study Objectives: Sleep fragmentation (SF) is an integral feature of sleep apnea and other prevalent sleep disorders. Although the effect of repetitive arousals on cognitive performance is well documented, the effects of long-term SF on electroencephalogra ...

American Academy of Sleep Medicine2015

Implications of the interplay between light and dark for human health in the built environment

Marilyne Andersen, María Lovísa Ámundadóttir

24-hour cycles of light and dark are one of the most significant factors in the built environment that affect human health and wellbeing. In addition to stimulating visual responses, light induces a range of circadian, physiological and behavioral response ...

2015

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Noyau suprachiasmatique

The genomic landscape of human cellular circadian variation points to a novel role for the signalosome

Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver

Transcriptional regulatory logic of the diurnal cycle in the mouse liver

PDF Signaling Is an Integral Part of the Drosophila Circadian Molecular Oscillator

Extensive Regulation of Diurnal Transcription and Metabolism by Glucocorticoids

Temperature regulates splicing efficiency of the cold-inducible RNA-binding protein gene Cirbp

Persistence, period and precision of autonomous cellular oscillators from the zebrafish segmentation clock

Sustained Sleep Fragmentation Induces Sleep Homeostasis in Mice

Comparison of acute non-visual bright light responses in patients with optic nerve disease, glaucoma and healthy controls

Implications of the interplay between light and dark for human health in the built environment

Graph Chatbot

Chattez avec Graph Search

Persistence, period and precision of autonomous cellular oscillators from the zebrafish segmentation clock

Comparison of acute non-visual bright light responses in patients with optic nerve disease, glaucoma and healthy controls

Temperature regulates splicing efficiency of the cold-inducible RNA-binding protein gene Cirbp

Implications of the interplay between light and dark for human health in the built environment

The genomic landscape of human cellular circadian variation points to a novel role for the signalosome

Transcriptional regulatory logic of the diurnal cycle in the mouse liver

Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver

PDF Signaling Is an Integral Part of the Drosophila Circadian Molecular Oscillator

Sustained Sleep Fragmentation Induces Sleep Homeostasis in Mice

Extensive Regulation of Diurnal Transcription and Metabolism by Glucocorticoids