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The present thesis work provides new insight into the generation of allylmetal species and into their reactivity toward electrophiles. endo-Allylpotassiums are known to be more stable than their corresponding exo-isomers. The ring strain of methylenecycloa ...
The elucidation of molecular cell-extracellular matrix (ECM) interactions regulating tissue dynamics necessitates straightforward model systems that can dissect the associated physiological complexity into a smaller number of distinct interactions. Here we ...
The identification of cell cycle-related genes is still a difficult task, even for organisms with relatively few genes such as the fission yeast. Several gene expression studies have been published on S. pombe showing similarities but also discrepancies in ...
The overall organization of cell division in Plasmodium is unique compared to that observed in model organisms because DNA replicates more than once per cell cycle at several points of its life cycle. The sequencing of the Plasmodium genome has also reveal ...
Cdc14 family phosphatases are highly conserved regulators of cell-cycle progression. Two of the best studied members of this family are budding yeast Cdc14p and its fission yeast homolog Clp1p/Flp1p. The function of both Saccharomyces cerevisiae Cdc14p and ...
Fault-tolerant control systems can be built by replicating critical components. However, replication raises the issue of inconsistency. Multiple protocols for ensuring consistency have been described in the literature. PADRE (Protocol for Asymmetric Duplex ...
When nutrients are abundant, S. pombe cells grow as rods, dividing by fission after formation of a medially placed cell wall or division septum. Septum formation is triggered by a group of proteins, called the septation initiation network or SIN, that trig ...
Fault-tolerant control systems can be built by replicating critical components. However, replication raises the issue of inconsistency. Multiple protocols for ensuring consistency have been described in the literature. PADRE (Protocol for Asymmetric Duplex ...
In today's systems, application are composed from various components that may be located on different machines. The components may have to collaborate in order to service a client request. More specifically, a client request to one component may trigger a ...
Fault-tolerant control systems can be built by replicating critical components. However, replication raises the issue of inconsistency. Multiple protocols for ensuring consistency have been described in the literature. PADRE (Protocol for Asymmetric Duplex ...