Publications associées à Noyau (biologie)

Computer simulations reveal mechanisms that organize nuclear dynein forces to separate centrosomes

Centrosome separation along the surface of the nucleus at the onset of mitosis is critical for bipolar spindle assembly. Dynein anchored on the nuclear envelope is known to be important for centrosome separation, but it is unclear how nuclear dynein forces ...

Amer Soc Cell Biology2017

The chromatin remodeling factor ISW-1 integrates organismal responses against nuclear and mitochondrial stress

Johan Auwerx, Maroun Bou Sleiman

Age-associated changes in chromatin structure have a major impact on organismal longevity. Despite being a central part of the ageing process, the organismal responses to the changes in chromatin organization remain unclear. Here we show that moderate dist ...

Nature Publishing Group2017

Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation

Paul Joseph Dyson, Tina Riedel, Benjamin Samuel Murray

The 'acidic patch' is a highly electronegative cleft on the histone H2A-H2B dimer in the nucleosome. It is a fundamental motif for protein binding and chromatin dynamics, but the cellular impact of targeting this potentially therapeutic site with exogenous ...

2017

Division site selection linked to inherited cell surface wave troughs in mycobacteria

Georg Fantner, John McKinney, Neeraj Dhar, Adrian Pascal Nievergelt, Pascal Damian Odermatt, Haig Alexander Eskandarian, Mélanie Thérèse Marie Hannebelle, Joëlle Xiao Yuan Ven

Cell division is tightly controlled in space and time to maintain cell size and ploidy within narrow bounds. In bacteria, the canonical Minicell (Min) and nucleoid occlusion (Noc) systems together ensure that division is restricted to midcell after complet ...

2017

Automated microfluidic sorting of mammalian cells labeled with magnetic microparticles for those that efficiently express and secrete a protein of interest

Amar Rida, Nicolas Mermod, Etienne Lançon, Niamh Harraghy

We developed a method for the fast sorting and selection of mammalian cells expressing and secreting a protein at high levels. This procedure relies on cell capture using an automated microfluidic device handling antibody-coupled magnetic microparticles an ...

Wiley2017

Mitonuclear communication in homeostasis and stress

Johan Auwerx, Adrienne Joëlle Laurence Mottis

Mitochondria participate in crucial cellular processes such as energy harvesting and intermediate metabolism. Although mitochondria possess their own genome - a vestige of their bacterial origins and endosymbiotic evolution - most mitochondrial proteins ar ...

Nature Publishing Group2016

Minimal model for spontaneous cell polarization and edge activity in oscillating, rotating and migrating cells

Jean-Jacques Meister, Chiara Gabella, Franck Claude Raynaud, Alicia Carine Bornert

How cells break symmetry and organize activity at their edges to move directionally is a fundamental question in cell biology. Physical models of cell motility commonly incorporate gradients of regulatory proteins and/or feedback from the motion itself to ...

Nature Publishing Group2016

Centriolar CPAP/SAS-4 Imparts Slow Processive Microtubule Growth

Pierre Gönczy, Nicola Jane Dynes, Ashwani Sharma

Centrioles are fundamental and evolutionarily conserved microtubule-based organelles whose assembly is characterized by microtubule growth rates that are orders of magnitude slower than those of cytoplasmic microtubules. Several centriolar proteins can int ...

2016

Highly efficient and gentle trapping of single cells in large microfluidic arrays for time-lapse experiments

Jürgen Brugger, Marco Grisi, Filiz Yesilköy

The isolation of single biological cells and their further cultivation in dedicated arrayed chambers are key to the collection of statistically reliable temporal data in cell-based biological experiments. In this work, we present a hydrodynamic single cell ...

Amer Inst Physics2016

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Noyau (biologie)

Computer simulations reveal mechanisms that organize nuclear dynein forces to separate centrosomes

The chromatin remodeling factor ISW-1 integrates organismal responses against nuclear and mitochondrial stress

Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation

Division site selection linked to inherited cell surface wave troughs in mycobacteria

A cockspur for the DSS cells: Erythrina crista-galli sensitizers

Automated microfluidic sorting of mammalian cells labeled with magnetic microparticles for those that efficiently express and secrete a protein of interest

Mitonuclear communication in homeostasis and stress

Minimal model for spontaneous cell polarization and edge activity in oscillating, rotating and migrating cells

Centriolar CPAP/SAS-4 Imparts Slow Processive Microtubule Growth

Highly efficient and gentle trapping of single cells in large microfluidic arrays for time-lapse experiments

Graph Chatbot

Chattez avec Graph Search

Computer simulations reveal mechanisms that organize nuclear dynein forces to separate centrosomes

Mitonuclear communication in homeostasis and stress

A cockspur for the DSS cells: Erythrina crista-galli sensitizers

The chromatin remodeling factor ISW-1 integrates organismal responses against nuclear and mitochondrial stress

Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation

Minimal model for spontaneous cell polarization and edge activity in oscillating, rotating and migrating cells

Automated microfluidic sorting of mammalian cells labeled with magnetic microparticles for those that efficiently express and secrete a protein of interest

Centriolar CPAP/SAS-4 Imparts Slow Processive Microtubule Growth

Highly efficient and gentle trapping of single cells in large microfluidic arrays for time-lapse experiments

Division site selection linked to inherited cell surface wave troughs in mycobacteria