Concept

Blastomère

Publications associées (20)

Unequal cleavage of the C. elegans zygote ensures robust embryogenesis

Asymmetric cell divisions play key roles in generating cellular diversity during embryogenesis, and in tissue homeostasis during postembryonic life. Particular asymmetric cell divisions producing differentially sized daughter cells were described in many s ...

EPFL2020

Enhancing developmental rate and quality of mouse single blastomeres into blastocysts using a microplatform

Philippe Renaud, Leila Montazeri, Hanie Kavand

The present work reports the beneficial effects of using a microplatform on the development of mouse single blastomeres (SBs) to the blastocyst stage. Development of blastocysts from SBs separated from two‐ and four‐cell stage embryos (two‐ and four‐cell S ...

2018

The relationship between low-temperature toughness and secondary crack in low-carbon bainitic weld metals

Roland Logé, Cyril Cayron, Gaojun Mao, Rui Cao

This paper aims to reveal the relationship among low-temperature toughness, microstructure and secondary crack from both microstructural and crystallographic perspectives. Instrumented Charpy tests were carried out in the upper platform, transition tempera ...

2018

Distinct mechanisms eliminate mother and daughter centrioles in meiosis of starfish oocytes

Pierre Gönczy

Centriole elimination is an essential process that occurs in female meiosis of metazoa to reset centriole number in the zygote at fertilization. How centrioles are eliminated remains poorly understood. Here we visualize the entire elimination process live ...

2016

Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages

Didier Trono, Anna Claire Groner

Mammalian development begins with the segregation of embryonic and extra-embryonic lineages in the blastocyst. Recent studies revealed cell-to-cell gene expression heterogeneity and dynamic cell rearrangements during mouse blastocyst formation. Thus, mecha ...

2015

PC7 and the related proteases Furin and Pace4 regulate E-cadherin function during blastocyst formation

Daniel Constam, Sylvain Frédéric Bessonnard

The first cell differentiation in mammalian embryos segregates polarized trophectoderm cells from an apolar inner cell mass (ICM). This lineage decision is specified in compacted morulae by cell polarization and adhesion acting on the Yes-associated protei ...

Rockefeller Univ Press2015

Culture of preantral follicles in poly(ethylene) glycol-based, three-dimensional hydrogel: a relationship between swelling ratio and follicular developments

Jeffrey Alan Hubbell, Seung Tae Lee

This study was undertaken to examine how the softness of poly(ethylene) glycol (PEG)-based hydrogels, creating a three-dimensional (3D) microenvironment, influences the in vitro growth of mouse ovarian follicles. Early secondary, preantral follicles of 2we ...

Wiley-Blackwell2015

Brittle and ductile crack-tip behavior in magnesium

William Curtin

The competition between dislocation emission and cleavage at a crack tip plays an important role in governing the intrinsic fracture behavior of crystalline materials. This competition is not well understood in magnesium, which has many different combinati ...

Elsevier2015

Polarity establishment, asymmetric division and segregation of fate determinants in early C. elegans embryos

Pierre Gönczy

Polarity establishment, asymmetric division, and acquisition of cell fates are critical steps during earlydevelopment. In this review, we discuss processes that set up the embryonic axes, with an emphasis onpolarity establishment and asymmetric division. W ...

WormBook2014

Asymmetric Cell Division in the Skin

Wan-Hung Fan

An asymmetric cell division (ACD) is defined as a division that gives rise to two daughter cells with different fates. It is the most common type of division during development. Analogous to Drosophila neuroblasts, proteins involved in ACD such as Insc and ...

EPFL2012

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