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Protofibrils are transient structures observed during in vitro formation of mature amyloid fibrils and have been implicated as the toxic species responsible for cell dysfunction and neuronal loss in Alzheimer's disease (AD) and other protein aggregation di ...
Employing a combined filtration and pptn. method, the endotoxin concn. in sodium alginate (SA) and sodium cellulose sulfate (SCS) was reduced to a value of 200 EU/g polymer. This is one-tenth of the regulatory threshold calcd., e.g., for an appropriate bio ...
To improve implant biocompatibility, we developed a simple cost-effective thermal surface treatment allowing an increase in the oxide layer thickness of a titanium (Ti) alloy used in orthopaedic implants. The goal of this study was to test in vitro the rea ...
A review. The ubiquitous use of poly(ethylene glycol) in the biomaterials field has also boosted the research activity in the chem. derivatization of this polymer. We focused our interest on the prepn. of tailor-made poly(ethylene glycol)-based structures ...
The effect of fibrin matrix micromorphology on neurite growth was investigated by measuring the length of neurites growing in three-dimensional fibrin gels with well characterized micromorphologies. Dorsal root ganglia (DRGs) from 7-day chick embryos were ...
The processing, mechanical analysis, and performance of functionally graded materials containing a metallic phase is reviewed in two parts. This first part focuses on processing, and distinguishes two principal process classes in graded materials productio ...
OBJECTIVE: To compare a novel resorbable hydrogel barrier with two previously studied barriers, oxidized regenerated cellulose and hyaluronic acid, for the prevention of postoperative adhesions. STUDY DESIGN: Two models were employed in the rat uterine hor ...
We present a new method for measuring the electrical resistivities of a stratified sample of thin biomaterials or tissue layers. The presented technique makes use of impedance measurements between It pairs of electrodes separated by varying distances. The ...
The elucidation of proteins involved in biomaterial-modulated macrophage behavior is crit. for the improvement of material performance and the initial exploration of material design capable of manipulating macrophage function for tissue engineering. Severa ...
Local, controlled induction of angiogenesis remains a challenge that limits tissue engineering approaches to replace or restore diseased tissues. We present a new class of bioactive synthetic hydrogel matrices based on poly(ethylene glycol) (PEG) and synth ...
