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The multidrug transporter ABCB1 (P-glycoprotein) is an ATP-binding cassette transporter that has a key role in protecting tissues from toxic insult and contributes to multidrug extrusion from cancer cells. Here, we report the near-atomic resolution cryo-EM ...
Proceedings of the National Academy of Sciences2018
Water uptake of gas shales is commonly considered one of the most important factors responsible for fluid loss during flowback operations after hydraulic fracturing. Imbibition experiments cover a key role in this context to analyze the impact of several f ...
Located at the shore of Geneva Lake, in Switzerland, the Chillon viaducts are two parallel structures consisted of post-tensioned concrete box girders, with a total length of 2 kilometers and 100m spans. Built in 1969, the bridges currently accommodate a t ...
Water uptake of gas shales is commonly considered one of the most important factors responsible for fluid loss during flowback operations after hydraulic fracturing. Imbibition experiments cover a key role in this context to analyze the impact of several f ...
Thermal loss and overheating caused by glazing is a key issue in reducing CO2 emission and energy consumption of buildings. A novel glazing based on micro compound parabolic concentrators (CPCs) is proposed. The glazing consists of a polymer layer with emb ...
Human ability to foresee the near future plays a key role in everyone's life to prevent potentially dangerous situations. To be able to make predictions is crucial when people have to interact with the surrounding environment. Modeling such capability can ...
Blockchain technology has the potential to decentralise many traditionally centralised systems. However, scalability remains a key challenge. A horizontally scalable solution, where performance increases by adding more nodes, would move blockchain systems ...
The renovation of existing buildings is one of the priorities of western countries and needs to be promoted to increase the current low renovation rate, estimated to be of 0.6% per year in the European and Swiss contexts. In parallel, the implementation of ...
Additive manufacturing is becoming one of the key methods for reproducing repair sections in remanufacturing processes. The major advantage of using additive processes is to minimize production time and waste. However, the surface quality and shape accurac ...
Graph filters, defined as polynomial functions of a graph-shift operator (GSO), play a key role in signal processing over graphs. In this work, we are interested in the adaptive and distributed estimation of graph filter coefficients from streaming graph s ...