Concept

Myoclonie

Publications associées (22)

Hardware Implementation of Digital Signal Processing Algorithms for Programmable Epilepsy Control Systems

Epilepsy is a common chronic neurological disorder that causes recurring seizures and affects more than 50 million people worldwide. Implantable medical devices (IMDs) are regarded as effective tools to cure patients who suffer from refractory epilepsy. Se ...

EPFL2023

Recent Developments on the Use of Nanomaterials for the Treatment of Epilepsy

Sandrine Gerber, Sara María Garcia Pedrero

Epilepsy affects more than 40 million people worldwide, constituting one of the most debilitating disorders of the Central Nervous System (CNS). It results from an imbalance in the electrical activity of neurons, which is primarily mediated by calcium ions ...

2022

Natural and targeted circuit reorganization after spinal cord injury

Grégoire Courtine, Jocelyne Bloch, Quentin Barraud, Jordan Squair, Mark Andrew Anderson, Claudia Kathe, Matthieu Pierre Gautier, Thomas Haynes Hutson

The authors summarize changes in circuits after spinal cord injury and current strategies to target these circuits in order to improve recovery, but also advocate for new concepts of reorganizing circuits informed by multi-omic single-cell atlases. A spina ...

NATURE PORTFOLIO2022

An automatized method to determine latencies of motor-evoked potentials under physiological and pathophysiological conditions

Friedhelm Christoph Hummel, Takuya Morishita, Pierre Theopistos Vassiliadis, Claudia Bigoni, Andéol Geoffroy Cadic-Melchior

Background. Latencies of motor evoked potentials (MEPs) can provide insights into the motor neuronal pathways activated by transcranial magnetic stimulation. Notwithstanding its clinical relevance, accurate, unbiased methods to automatize latency detection ...

IOP Publishing Ltd2022

Mechanotaxis directs Pseudomonas aeruginosa twitching motility

Alexandre Louis André Persat, Lorenzo Anton-Louis Talà, Xavier Jean-Yves Pierrat, Jose Negrete Jr, Joanne Netter Engel, Marco Julian Kühn

The opportunistic pathogen Pseudomonas aeruginosa explores surfaces using twitching motility powered by retractile extracellu-lar filaments called type IV pili (T4P). Single cells twitch by sequen-tial T4P extension, attachment, and retraction. How single ...

NATL ACAD SCIENCES2021

Self-Aware Anomaly-Detection for Epilepsy Monitoring on Low-Power Wearable Electrocardiographic Devices

David Atienza Alonso, Amir Aminifar, Tomas Teijeiro Campo, Farnaz Forooghifar

Low-power wearable technologies offer a promising solution to pervasive epilepsy monitoring by removing the constraints concerning time and location, on one hand, and fulfilling long-term tracking, on the other hand. In the case of epileptic seizures, as t ...

2021

Development of a peripheral neuroprosthesis to elicit fine hand movements in primates

Marion Aimée Geneviève Badi-Dubois

Neurological disorders such as spinal cord lesion and stroke disturb sensorimotor pathways and result in severe motor deficits that can dreadfully impact the quality of life of affected individuals. Strategies aiming at restoring hand function after upper- ...

EPFL2021

Robot-induced hallucinations in Parkinson’s disease depend on altered sensorimotor processing in fronto-temporal network

Dimitri Nestor Alice Van De Ville, Olaf Blanke, Fosco Bernasconi, Jevita Potheegadoo, Michel Akselrod, Nathan Quentin Faivre, Giulio Rognini, Masayuki Hara, Michela Bassolino, Eva Blondiaux, Giedre Stripeikyte, Matteo Franza, Stéphanie Konik

Hallucinations in Parkinson’s disease (PD) are disturbing and frequent non-motor symptoms and constitute a major risk factor for psychosis and dementia. We report a robotics-based approach applying conflicting sensorimotor stimulation, enabling the inducti ...

2021

Noninvasive detection of focal seizures in ambulatory patients

David Atienza Alonso, Leila Cammoun

Reliably detecting focal seizures without secondary generalization during daily life activities, chronically, using convenient portable or wearable devices, would offer patients with active epilepsy a number of potential benefits, such as providing more re ...

2020

Dynamic analysis of fMRI activation during epileptic spikes can help identify the seizure origin

Amir Hossein Omidvarnia

Objective We use the dynamic electroencephalography-functional magnetic resonance imaging (EEG-fMRI) method to incorporate variability in the amplitude and field of the interictal epileptic discharges (IEDs) into the fMRI analysis. We ask whether IED varia ...

2020

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